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G(s)alpha deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency.
Chen M, Feng HZ, Gupta D, Kelleher J, Dickerson KE, Wang J, Hunt D, Jou W, Gavrilova O, Jin JP, Weinstein LS. Chen M, et al. Among authors: feng hz. Am J Physiol Cell Physiol. 2009 Apr;296(4):C930-40. doi: 10.1152/ajpcell.00443.2008. Epub 2009 Jan 21. Am J Physiol Cell Physiol. 2009. PMID: 19158402 Free PMC article.
Improved fatigue resistance in Gsα-deficient and aging mouse skeletal muscles due to adaptive increases in slow fibers.
Feng HZ, Chen M, Weinstein LS, Jin JP. Feng HZ, et al. J Appl Physiol (1985). 2011 Sep;111(3):834-43. doi: 10.1152/japplphysiol.00031.2011. Epub 2011 Jun 16. J Appl Physiol (1985). 2011. PMID: 21680879 Free PMC article.
Genetically modified mice with deficiency of the G protein alpha-subunit (G(s)alpha) in skeletal muscle showed metabolic abnormality with reduced glucose tolerance, low muscle mass, and low contractile force, along with a fast-to-slow-fiber-type switch (Chen M, Feng HZ …
Genetically modified mice with deficiency of the G protein alpha-subunit (G(s)alpha) in skeletal muscle showed metabolic abnormality with re …
Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching.
Ikonomov OC, Sbrissa D, Delvecchio K, Feng HZ, Cartee GD, Jin JP, Shisheva A. Ikonomov OC, et al. Among authors: feng hz. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E119-31. doi: 10.1152/ajpendo.00030.2013. Epub 2013 May 14. Am J Physiol Endocrinol Metab. 2013. PMID: 23673157 Free PMC article.
Development of dilated cardiomyopathy in Bmal1-deficient mice.
Lefta M, Campbell KS, Feng HZ, Jin JP, Esser KA. Lefta M, et al. Among authors: feng hz. Am J Physiol Heart Circ Physiol. 2012 Aug 15;303(4):H475-85. doi: 10.1152/ajpheart.00238.2012. Epub 2012 Jun 15. Am J Physiol Heart Circ Physiol. 2012. PMID: 22707558 Free PMC article.
70 results