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Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.
Shi ZC, Devasagayaraj A, Gu K, Jin H, Marinelli B, Samala L, Scott S, Stouch T, Tunoori A, Wang Y, Zang Y, Zhang C, Kimball SD, Main AJ, Sun W, Yang Q, Nouraldeen A, Yu XQ, Buxton E, Patel S, Nguyen N, Swaffield J, Powell DR, Wilson A, Liu Q. Shi ZC, et al. Among authors: buxton e. J Med Chem. 2008 Jul 10;51(13):3684-7. doi: 10.1021/jm800338j. Epub 2008 Jun 17. J Med Chem. 2008. PMID: 18557609
High-throughput mouse knockouts provide a functional analysis of the genome.
Friddle CJ, Abuin A, Ramirez-Solis R, Richter LJ, Buxton EC, Edwards J, Finch RA, Gupta A, Hansen G, Holt KH, Hu Y, Huang W, Jaing C, Key BW Jr, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Newhouse M, Perry T, Platt KA, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Tran D, Wann ER, Walke W, Wallace JD, Xu N, Zhu Q, Person C, Sands AT, Zambrowicz BP. Friddle CJ, et al. Among authors: buxton ec. Cold Spring Harb Symp Quant Biol. 2003;68:311-5. doi: 10.1101/sqb.2003.68.311. Cold Spring Harb Symp Quant Biol. 2003. PMID: 15338631 No abstract available.
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW Jr, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT. Zambrowicz BP, et al. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14. doi: 10.1073/pnas.2336103100. Epub 2003 Nov 10. Proc Natl Acad Sci U S A. 2003. PMID: 14610273 Free PMC article.
Elucidating key determinants of engineered scFv antibody in MMP-9 binding using high throughput screening and machine learning.
Kalantar M, Kalanther I, Kumar S, Buxton EK, Raeeszadeh-Sarmazdeh M. Kalantar M, et al. Among authors: buxton ek. bioRxiv [Preprint]. 2024 Jun 6:2024.06.04.597476. doi: 10.1101/2024.06.04.597476. bioRxiv. 2024. Update in: Comput Struct Biotechnol J. 2024 Oct 10;23:3759-3770. doi: 10.1016/j.csbj.2024.10.005 PMID: 38895413 Free PMC article. Updated. Preprint.
Visual impairment among eye health workers in a tertiary eye centre in Ghana.
Tagoe NN, Abaidoo B, Fordjuor G, Seidu YA, Acquah SA, Akafo AE, Buxton E, Fiadoyor D, Afenyo G, Asiedu SO, Essuman VA. Tagoe NN, et al. Among authors: buxton e. Ghana Med J. 2021 Dec;55(4):278-284. doi: 10.4314/gmj.v55i4.8. Ghana Med J. 2021. PMID: 35957937 Free PMC article.
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