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The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.
Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, Harris AL, Fox SB. Tan EY, et al. Among authors: fox sb. Br J Cancer. 2009 Jan 27;100(2):405-11. doi: 10.1038/sj.bjc.6604844. Br J Cancer. 2009. PMID: 19165203 Free PMC article.
Thymidine phosphorylase is angiogenic and promotes tumor growth.
Moghaddam A, Zhang HT, Fan TP, Hu DE, Lees VC, Turley H, Fox SB, Gatter KC, Harris AL, Bicknell R. Moghaddam A, et al. Among authors: fox sb. Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):998-1002. doi: 10.1073/pnas.92.4.998. Proc Natl Acad Sci U S A. 1995. PMID: 7532308 Free PMC article.
357 results