Spielmann H - Search Results

1

Embryonic stem cell test remastered: comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro.

Buesen R, Genschow E, Slawik B, Visan A, Spielmann H, Luch A, Seiler A. Buesen R, et al. Among authors: spielmann h. Toxicol Sci. 2009 Apr;108(2):389-400. doi: 10.1093/toxsci/kfp012. Epub 2009 Jan 23. Toxicol Sci. 2009. PMID: 19168572

2

[Improving the embryonic stem cell test (EST) by establishing molecular endpoints of tissue specific development using murine embryonic stem cells (D3 cells)].

Seiler A, Visan A, Pohl I, Genschow E, Buesen R, Spielmann H. Seiler A, et al. Among authors: spielmann h. ALTEX. 2002;19 Suppl 1:55-63. ALTEX. 2002. PMID: 12096331 German.

3

Trends in improving the embryonic stem cell test (EST): an overview.

Buesen R, Visan A, Genschow E, Slawik B, Spielmann H, Seiler A. Buesen R, et al. Among authors: spielmann h. ALTEX. 2004;21(1):15-22. ALTEX. 2004. PMID: 14976585 Free article. Review.

4

Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test.

Seiler A, Visan A, Buesen R, Genschow E, Spielmann H. Seiler A, et al. Among authors: spielmann h. Reprod Toxicol. 2004 Mar-Apr;18(2):231-40. doi: 10.1016/j.reprotox.2003.10.015. Reprod Toxicol. 2004. PMID: 15019721

5

Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests.

Genschow E, Spielmann H, Scholz G, Pohl I, Seiler A, Clemann N, Bremer S, Becker K. Genschow E, et al. Among authors: spielmann h. Altern Lab Anim. 2004 Sep;32(3):209-44. doi: 10.1177/026119290403200305. Altern Lab Anim. 2004. PMID: 15588166

6

Use of murine embryonic stem cells in embryotoxicity assays: the embryonic stem cell test.

Seiler AE, Buesen R, Visan A, Spielmann H. Seiler AE, et al. Among authors: spielmann h. Methods Mol Biol. 2006;329:371-95. doi: 10.1385/1-59745-037-5:371. Methods Mol Biol. 2006. PMID: 16846005

7

The embryonic stem cell test as tool to assess structure-dependent teratogenicity: the case of valproic acid.

Riebeling C, Pirow R, Becker K, Buesen R, Eikel D, Kaltenhäuser J, Meyer F, Nau H, Slawik B, Visan A, Volland J, Spielmann H, Luch A, Seiler A. Riebeling C, et al. Among authors: spielmann h. Toxicol Sci. 2011 Apr;120(2):360-70. doi: 10.1093/toxsci/kfr001. Epub 2011 Jan 11. Toxicol Sci. 2011. PMID: 21227905 Free PMC article.

8

Defined culture medium for stem cell differentiation: applicability of serum-free conditions in the mouse embryonic stem cell test.

Riebeling C, Schlechter K, Buesen R, Spielmann H, Luch A, Seiler A. Riebeling C, et al. Among authors: spielmann h. Toxicol In Vitro. 2011 Jun;25(4):914-21. doi: 10.1016/j.tiv.2011.02.013. Epub 2011 Mar 3. Toxicol In Vitro. 2011. PMID: 21376803

9

The validated embryonic stem cell test to predict embryotoxicity in vitro.

Seiler AE, Spielmann H. Seiler AE, et al. Among authors: spielmann h. Nat Protoc. 2011 Jun 16;6(7):961-78. doi: 10.1038/nprot.2011.348. Nat Protoc. 2011. PMID: 21720311

10

Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.

Riebeling C, Hayess K, Peters AK, Steemans M, Spielmann H, Luch A, Seiler AE. Riebeling C, et al. Among authors: spielmann h. Crit Rev Toxicol. 2012 May;42(5):443-64. doi: 10.3109/10408444.2012.674483. Crit Rev Toxicol. 2012. PMID: 22512667 Review.

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