Holcombe RF - Search Results

1

WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells.

Tang Y, Simoneau AR, Liao WX, Yi G, Hope C, Liu F, Li S, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang BH, Zi X. Tang Y, et al. Among authors: holcombe rf. Mol Cancer Ther. 2009 Feb;8(2):458-68. doi: 10.1158/1535-7163.MCT-08-0885. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174556 Free PMC article.

2

Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness.

Zi X, Guo Y, Simoneau AR, Hope C, Xie J, Holcombe RF, Hoang BH. Zi X, et al. Among authors: holcombe rf. Cancer Res. 2005 Nov 1;65(21):9762-70. doi: 10.1158/0008-5472.CAN-05-0103. Cancer Res. 2005. PMID: 16266997

3

Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression.

Nguyen A, Rosner A, Milovanovic T, Hope C, Planutis K, Saha B, Chaiwun B, Lin F, Imam SA, Marsh JL, Holcombe RF. Nguyen A, et al. Among authors: holcombe rf. Int J Oncol. 2005 Oct;27(4):949-56. Int J Oncol. 2005. PMID: 16142310

4

Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells.

Guo Y, Zi X, Koontz Z, Kim A, Xie J, Gorlick R, Holcombe RF, Hoang BH. Guo Y, et al. Among authors: holcombe rf. J Orthop Res. 2007 Jul;25(7):964-71. doi: 10.1002/jor.20356. J Orthop Res. 2007. PMID: 17318900 Free article.

5

Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancer.

Dellinger TH, Planutis K, Jandial DD, Eskander RN, Martinez ME, Zi X, Monk BJ, Holcombe RF. Dellinger TH, et al. Among authors: holcombe rf. Gynecol Oncol. 2012 Aug;126(2):259-67. doi: 10.1016/j.ygyno.2012.04.026. Epub 2012 Apr 30. Gynecol Oncol. 2012. PMID: 22555103 Free PMC article.

6

Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma.

Milovanovic T, Planutis K, Nguyen A, Marsh JL, Lin F, Hope C, Holcombe RF. Milovanovic T, et al. Among authors: holcombe rf. Int J Oncol. 2004 Nov;25(5):1337-42. Int J Oncol. 2004. PMID: 15492823

7

Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease.

You XJ, Bryant PJ, Jurnak F, Holcombe RF. You XJ, et al. Among authors: holcombe rf. Oncol Rep. 2007 Sep;18(3):691-4. Oncol Rep. 2007. PMID: 17671721

8

Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention.

Hope C, Planutis K, Planutiene M, Moyer MP, Johal KS, Woo J, Santoso C, Hanson JA, Holcombe RF. Hope C, et al. Among authors: holcombe rf. Mol Nutr Food Res. 2008 Jun;52 Suppl 1(Suppl 1):S52-61. doi: 10.1002/mnfr.200700448. Mol Nutr Food Res. 2008. PMID: 18504708 Free PMC article.

9

Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer.

Nguyen AV, Martinez M, Stamos MJ, Moyer MP, Planutis K, Hope C, Holcombe RF. Nguyen AV, et al. Among authors: holcombe rf. Cancer Manag Res. 2009 Apr 3;1:25-37. Cancer Manag Res. 2009. PMID: 21188121 Free PMC article.

10

Wnt signaling in ovarian tumorigenesis.

Gatcliffe TA, Monk BJ, Planutis K, Holcombe RF. Gatcliffe TA, et al. Among authors: holcombe rf. Int J Gynecol Cancer. 2008 Sep-Oct;18(5):954-62. doi: 10.1111/j.1525-1438.2007.01127.x. Epub 2007 Nov 6. Int J Gynecol Cancer. 2008. PMID: 17986238 Free PMC article. Review.

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