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Non-anticoagulant heparins and inhibition of cancer.
Casu B, Vlodavsky I, Sanderson RD. Casu B, et al. Among authors: sanderson rd. Pathophysiol Haemost Thromb. 2008;36(3-4):195-203. doi: 10.1159/000175157. Epub 2009 Jan 27. Pathophysiol Haemost Thromb. 2008. PMID: 19176992 Free PMC article. Review.
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD. Yang Y, et al. Among authors: sanderson rd. Blood. 2007 Sep 15;110(6):2041-8. doi: 10.1182/blood-2007-04-082495. Epub 2007 May 29. Blood. 2007. PMID: 17536013 Free PMC article.
Heparanase: busy at the cell surface.
Fux L, Ilan N, Sanderson RD, Vlodavsky I. Fux L, et al. Among authors: sanderson rd. Trends Biochem Sci. 2009 Oct;34(10):511-9. doi: 10.1016/j.tibs.2009.06.005. Epub 2009 Sep 3. Trends Biochem Sci. 2009. PMID: 19733083 Free PMC article. Review.
SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.
Ritchie JP, Ramani VC, Ren Y, Naggi A, Torri G, Casu B, Penco S, Pisano C, Carminati P, Tortoreto M, Zunino F, Vlodavsky I, Sanderson RD, Yang Y. Ritchie JP, et al. Among authors: sanderson rd. Clin Cancer Res. 2011 Mar 15;17(6):1382-93. doi: 10.1158/1078-0432.CCR-10-2476. Epub 2011 Jan 21. Clin Cancer Res. 2011. PMID: 21257720 Free PMC article.
The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.
Ramani VC, Purushothaman A, Stewart MD, Thompson CA, Vlodavsky I, Au JL, Sanderson RD. Ramani VC, et al. Among authors: sanderson rd. FEBS J. 2013 May;280(10):2294-306. doi: 10.1111/febs.12168. Epub 2013 Mar 4. FEBS J. 2013. PMID: 23374281 Free PMC article. Review.
135 results