Ranheim EA - Search Results

1

Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia.

Wu QL, Zierold C, Ranheim EA. Wu QL, et al. Among authors: ranheim ea. Blood. 2009 Mar 26;113(13):3031-9. doi: 10.1182/blood-2008-06-163303. Epub 2009 Jan 28. Blood. 2009. PMID: 19179304 Free PMC article.

2

Frizzled 9 knock-out mice have abnormal B-cell development.

Ranheim EA, Kwan HC, Reya T, Wang YK, Weissman IL, Francke U. Ranheim EA, et al. Blood. 2005 Mar 15;105(6):2487-94. doi: 10.1182/blood-2004-06-2334. Epub 2004 Nov 30. Blood. 2005. PMID: 15572594 Free article.

3

Tumoricidal effects of activated macrophages in a mouse model of chronic lymphocytic leukemia.

Wu QL, Buhtoiarov IN, Sondel PM, Rakhmilevich AL, Ranheim EA. Wu QL, et al. Among authors: ranheim ea. J Immunol. 2009 Jun 1;182(11):6771-8. doi: 10.4049/jimmunol.0801847. J Immunol. 2009. PMID: 19454672 Free PMC article.

4

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.

Wang J, Liu Y, Li Z, Wang Z, Tan LX, Ryu MJ, Meline B, Du J, Young KH, Ranheim E, Chang Q, Zhang J. Wang J, et al. Blood. 2011 Jul 14;118(2):368-79. doi: 10.1182/blood-2010-12-326058. Epub 2011 May 17. Blood. 2011. PMID: 21586752 Free PMC article.

5

Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis.

Wang J, Liu Y, Tan LX, Lo JC, Du J, Ryu MJ, Ranheim EA, Zhang J. Wang J, et al. Among authors: ranheim ea. Cell Cycle. 2011 Sep 1;10(17):2836-9. doi: 10.4161/cc.10.17.17195. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21857161 Free PMC article.

6

Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Kong G, Du J, Liu Y, Meline B, Chang YI, Ranheim EA, Wang J, Zhang J. Kong G, et al. Among authors: ranheim ea. J Biol Chem. 2013 Jun 21;288(25):18219-27. doi: 10.1074/jbc.M113.475376. Epub 2013 May 14. J Biol Chem. 2013. PMID: 23673656 Free PMC article.

7

Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions.

Wang J, Kong G, Liu Y, Du J, Chang YI, Tey SR, Zhang X, Ranheim EA, Saba-El-Leil MK, Meloche S, Damnernsawad A, Zhang J, Zhang J. Wang J, et al. Among authors: ranheim ea. Blood. 2013 Jun 27;121(26):5203-7. doi: 10.1182/blood-2012-12-475863. Epub 2013 May 17. Blood. 2013. PMID: 23687087 Free PMC article.

8

Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.

Chang YI, You X, Kong G, Ranheim EA, Wang J, Du J, Liu Y, Zhou Y, Ryu MJ, Zhang J. Chang YI, et al. Among authors: ranheim ea. Leukemia. 2015 Sep;29(9):1847-56. doi: 10.1038/leu.2015.85. Epub 2015 Mar 24. Leukemia. 2015. PMID: 25801914 Free PMC article.

9

Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.

Kong G, Chang YI, Damnernsawad A, You X, Du J, Ranheim EA, Lee W, Ryu MJ, Zhou Y, Xing Y, Chang Q, Burd CE, Zhang J. Kong G, et al. Among authors: ranheim ea. Leukemia. 2016 Jul;30(7):1542-51. doi: 10.1038/leu.2016.40. Epub 2016 Feb 29. Leukemia. 2016. PMID: 27055865 Free PMC article.

10

p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.

Zhang J, Kong G, Rajagopalan A, Lu L, Song J, Hussaini M, Zhang X, Ranheim EA, Liu Y, Wang J, Gao X, Chang YI, Johnson KD, Zhou Y, Yang D, Bhatnagar B, Lucas DM, Bresnick EH, Zhong X, Padron E, Zhang J. Zhang J, et al. Among authors: ranheim ea. Blood. 2017 Jan 19;129(3):358-370. doi: 10.1182/blood-2016-06-719237. Epub 2016 Nov 4. Blood. 2017. PMID: 27815262 Free PMC article.

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