Nomoto M - Search Results

1

Bile acid-induced elevated oxidative stress in the absence of farnesoid X receptor.

Nomoto M, Miyata M, Yin S, Kurata Y, Shimada M, Yoshinari K, Gonzalez FJ, Suzuki K, Shibasaki S, Kurosawa T, Yamazoe Y. Nomoto M, et al. Biol Pharm Bull. 2009 Feb;32(2):172-8. doi: 10.1248/bpb.32.172. Biol Pharm Bull. 2009. PMID: 19182371 Free PMC article.

2

ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output.

Nomoto M, Miyata M, Shimada M, Yoshinari K, Gonzalez FJ, Shibasaki S, Kurosawa T, Shindo Y, Yamazoe Y. Nomoto M, et al. Eur J Pharmacol. 2007 Nov 28;574(2-3):192-200. doi: 10.1016/j.ejphar.2007.07.004. Epub 2007 Jul 10. Eur J Pharmacol. 2007. PMID: 17651726

3

Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption.

Miyata M, Matsuda Y, Nomoto M, Takamatsu Y, Sato N, Hamatsu M, Dawson PA, Gonzalez FJ, Yamazoe Y. Miyata M, et al. Among authors: nomoto m. Drug Metab Dispos. 2009 Feb;37(2):338-44. doi: 10.1124/dmd.108.022590. Epub 2008 Nov 6. Drug Metab Dispos. 2009. PMID: 18988759 Free PMC article.

4

Possible protective role of pregnenolone-16 alpha-carbonitrile in lithocholic acid-induced hepatotoxicity through enhanced hepatic lipogenesis.

Miyata M, Nomoto M, Sotodate F, Mizuki T, Hori W, Nagayasu M, Yokokawa S, Ninomiya S, Yamazoe Y. Miyata M, et al. Among authors: nomoto m. Eur J Pharmacol. 2010 Jun 25;636(1-3):145-54. doi: 10.1016/j.ejphar.2010.03.022. Epub 2010 Mar 30. Eur J Pharmacol. 2010. PMID: 20359477

5

Physiological models are good tools to predict rat bioavailability of EF5154 prodrugs from in vitro intestinal parameters.

Nomoto M, Tatebayashi T, Morita J, Suzuki H, Aizawa K, Kurosawa T, Komiya I. Nomoto M, et al. J Pharm Sci. 2009 Apr;98(4):1532-44. doi: 10.1002/jps.21510. J Pharm Sci. 2009. PMID: 18683862

6

Enhancement of fibrinolysis by EF6265 [(S)-7-amino-2-[[[(R)-2-methyl-1-(3-phenylpropanoylamino)propyl]hydroxyphosphinoyl] methyl]heptanoic acid], a specific inhibitor of plasma carboxypeptidase B.

Suzuki K, Muto Y, Fushihara K, Kanemoto K, Iida H, Sato E, Kikuchi C, Matsushima T, Kato E, Nomoto M, Yoshioka S, Ishii H. Suzuki K, et al. Among authors: nomoto m. J Pharmacol Exp Ther. 2004 May;309(2):607-15. doi: 10.1124/jpet.103.062729. Epub 2004 Feb 4. J Pharmacol Exp Ther. 2004. PMID: 14762098

7

Stimulation of nitric oxide synthase during oxidative endothelial cell injury.

Shimizu S, Nomoto M, Naito S, Yamamoto T, Momose K. Shimizu S, et al. Among authors: nomoto m. Biochem Pharmacol. 1998 Jan 1;55(1):77-83. doi: 10.1016/s0006-2952(97)00399-7. Biochem Pharmacol. 1998. PMID: 9413933

8

Improvement of intestinal absorption of peptide drugs by glycosylation: transport of tetrapeptide by the sodium ion-dependent D-glucose transporter.

Nomoto M, Yamada K, Haga M, Hayashi M. Nomoto M, et al. J Pharm Sci. 1998 Mar;87(3):326-32. doi: 10.1021/js970269p. J Pharm Sci. 1998. PMID: 9523986

9

Pharmacokinetic Bioequivalence, Safety, and Immunogenicity of DMB-3111, a Trastuzumab Biosimilar, and Trastuzumab in Healthy Japanese Adult Males: Results of a Randomized Trial.

Morita J, Tanaka M, Nomoto M, Matsuki S, Tsuru T, Matsuguma K, Shiramoto M. Morita J, et al. Among authors: nomoto m. BioDrugs. 2016 Feb;30(1):17-25. doi: 10.1007/s40259-015-0153-2. BioDrugs. 2016. PMID: 26691837 Free PMC article. Clinical Trial.

10

Delayed L-DOPA-induced hyperalgesia.

Shimizu T, Iwata S, Miyata A, Fukuda T, Nomoto M. Shimizu T, et al. Among authors: nomoto m. Pharmacol Biochem Behav. 2006 Nov;85(3):643-7. doi: 10.1016/j.pbb.2006.10.020. Epub 2006 Dec 4. Pharmacol Biochem Behav. 2006. PMID: 17141847

Previously we reported on L-DOPA's antinociceptive effect on substance P-induced nociceptive behaviors in mice [Shimizu T, Iwata S, Morioka H, Masuyama T, Fukuda T, Nomoto M. Antinociceptive mechanism of L-DOPA. Pain 2004;110;246-9.]. Since significant hyperalgesia …

Previously we reported on L-DOPA's antinociceptive effect on substance P-induced nociceptive behaviors in mice [Shimizu T, Iwata S, Morioka …

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