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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Among authors: ashworth a. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.
DNA repair deficiency as a therapeutic target in cancer.
Martin SA, Lord CJ, Ashworth A. Martin SA, et al. Among authors: ashworth a. Curr Opin Genet Dev. 2008 Feb;18(1):80-6. doi: 10.1016/j.gde.2008.01.016. Epub 2008 Mar 14. Curr Opin Genet Dev. 2008. PMID: 18343102 Review.
Targeted therapy for cancer using PARP inhibitors.
Lord CJ, Ashworth A. Lord CJ, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2008 Aug;8(4):363-9. doi: 10.1016/j.coph.2008.06.016. Curr Opin Pharmacol. 2008. PMID: 18644251 Review.
Therapeutic targeting of the DNA mismatch repair pathway.
Martin SA, Lord CJ, Ashworth A. Martin SA, et al. Among authors: ashworth a. Clin Cancer Res. 2010 Nov 1;16(21):5107-13. doi: 10.1158/1078-0432.CCR-10-0821. Epub 2010 Sep 7. Clin Cancer Res. 2010. PMID: 20823149 Review.
846 results