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Mutant presenilin 1 increases the expression and activity of BACE1.
Giliberto L, Borghi R, Piccini A, Mangerini R, Sorbi S, Cirmena G, Garuti A, Ghetti B, Tagliavini F, Mughal MR, Mattson MP, Zhu X, Wang X, Guglielmotto M, Tamagno E, Tabaton M. Giliberto L, et al. Among authors: garuti a. J Biol Chem. 2009 Apr 3;284(14):9027-38. doi: 10.1074/jbc.M805685200. Epub 2009 Feb 5. J Biol Chem. 2009. PMID: 19196715 Free PMC article.
HMGA2 overexpression in polycythemia vera with t(12;21)(q14;q22).
Aliano S, Cirmena G, Garuti A, Fugazza G, Bruzzone R, Rocco I, Malacarne M, Ballestrero A, Sessarego M. Aliano S, et al. Among authors: garuti a. Cancer Genet Cytogenet. 2007 Sep;177(2):115-9. doi: 10.1016/j.cancergencyto.2007.05.009. Cancer Genet Cytogenet. 2007. PMID: 17854665
Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia.
Carella AM, Garuti A, Cirmena G, Catania G, Rocco I, Palermo C, Pica G, Pierri I, Miglino M, Ballestrero A, Gobbi M, Patrone F. Carella AM, et al. Among authors: garuti a. Leuk Lymphoma. 2010 Feb;51(2):275-8. doi: 10.3109/10428190903503446. Leuk Lymphoma. 2010. PMID: 20038234
Ras-induced resistance to lapatinib is overcome by MEK inhibition.
Zoppoli G, Moran E, Soncini D, Cea M, Garuti A, Rocco I, Cirmena G, Grillo V, Bagnasco L, Icardi G, Ansaldi F, Parodi S, Patrone F, Ballestrero A, Nencioni A. Zoppoli G, et al. Among authors: garuti a. Curr Cancer Drug Targets. 2010 Mar;10(2):168-75. doi: 10.2174/156800910791054211. Curr Cancer Drug Targets. 2010. PMID: 20088787
β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.
Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. Piccini A, et al. Among authors: garuti a. J Neurochem. 2012 Sep;122(5):1023-31. doi: 10.1111/j.1471-4159.2012.07834.x. Epub 2012 Jul 11. J Neurochem. 2012. PMID: 22708832 Free article.
71 results