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Page 1
Crystal structure of human prion protein bound to a therapeutic antibody.
Antonyuk SV, Trevitt CR, Strange RW, Jackson GS, Sangar D, Batchelor M, Cooper S, Fraser C, Jones S, Georgiou T, Khalili-Shirazi A, Clarke AR, Hasnain SS, Collinge J. Antonyuk SV, et al. Among authors: trevitt cr. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2554-8. doi: 10.1073/pnas.0809170106. Epub 2009 Feb 9. Proc Natl Acad Sci U S A. 2009. PMID: 19204296 Free PMC article.
The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC.
Hosszu LL, Jackson GS, Trevitt CR, Jones S, Batchelor M, Bhelt D, Prodromidou K, Clarke AR, Waltho JP, Collinge J. Hosszu LL, et al. Among authors: trevitt cr. J Biol Chem. 2004 Jul 2;279(27):28515-21. doi: 10.1074/jbc.M313762200. Epub 2004 Apr 27. J Biol Chem. 2004. PMID: 15123682 Free article.
Folding kinetics of the human prion protein probed by temperature jump.
Hart T, Hosszu LL, Trevitt CR, Jackson GS, Waltho JP, Collinge J, Clarke AR. Hart T, et al. Among authors: trevitt cr. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5651-6. doi: 10.1073/pnas.0811457106. Epub 2009 Mar 24. Proc Natl Acad Sci U S A. 2009. PMID: 19321423 Free PMC article.
Conformational properties of beta-PrP.
Hosszu LLP, Trevitt CR, Jones S, Batchelor M, Scott DJ, Jackson GS, Collinge J, Waltho JP, Clarke AR. Hosszu LLP, et al. Among authors: trevitt cr. J Biol Chem. 2009 Aug 14;284(33):21981-21990. doi: 10.1074/jbc.M809173200. Epub 2009 Apr 15. J Biol Chem. 2009. PMID: 19369250 Free PMC article.
Pharmacological chaperone for the structured domain of human prion protein.
Nicoll AJ, Trevitt CR, Tattum MH, Risse E, Quarterman E, Ibarra AA, Wright C, Jackson GS, Sessions RB, Farrow M, Waltho JP, Clarke AR, Collinge J. Nicoll AJ, et al. Among authors: trevitt cr. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17610-5. doi: 10.1073/pnas.1009062107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876144 Free PMC article.
N-terminal domain of prion protein directs its oligomeric association.
Trevitt CR, Hosszu LL, Batchelor M, Panico S, Terry C, Nicoll AJ, Risse E, Taylor WA, Sandberg MK, Al-Doujaily H, Linehan JM, Saibil HR, Scott DJ, Collinge J, Waltho JP, Clarke AR. Trevitt CR, et al. J Biol Chem. 2014 Sep 12;289(37):25497-508. doi: 10.1074/jbc.M114.566588. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074940 Free PMC article.
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