Harvey M - Search Results

1

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

Ménard V, Girard H, Harvey M, Pérusse L, Guillemette C. Ménard V, et al. Among authors: harvey m. Hum Mutat. 2009 Apr;30(4):677-87. doi: 10.1002/humu.20946. Hum Mutat. 2009. PMID: 19204906

2

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

Ménard V, Eap O, Harvey M, Guillemette C, Lévesque E. Ménard V, et al. Among authors: harvey m. Hum Mutat. 2009 Sep;30(9):1310-9. doi: 10.1002/humu.21054. Hum Mutat. 2009. PMID: 19572376

3

UGT genomic diversity: beyond gene duplication.

Guillemette C, Lévesque E, Harvey M, Bellemare J, Menard V. Guillemette C, et al. Among authors: harvey m. Drug Metab Rev. 2010 Feb;42(1):24-44. doi: 10.3109/03602530903210682. Drug Metab Rev. 2010. PMID: 19857043 Free article. Review.

4

A novel UGT1 marker associated with better tolerance against irinotecan-induced severe neutropenia in metastatic colorectal cancer patients.

Chen S, Laverdiere I, Tourancheau A, Jonker D, Couture F, Cecchin E, Villeneuve L, Harvey M, Court MH, Innocenti F, Toffoli G, Lévesque E, Guillemette C. Chen S, et al. Among authors: harvey m. Pharmacogenomics J. 2015 Dec;15(6):513-20. doi: 10.1038/tpj.2015.12. Epub 2015 Mar 17. Pharmacogenomics J. 2015. PMID: 25778466 Free PMC article.

5

Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.

Bellemare J, Rouleau M, Harvey M, Guillemette C. Bellemare J, et al. Among authors: harvey m. J Biol Chem. 2010 Feb 5;285(6):3600-3607. doi: 10.1074/jbc.M109.083139. Epub 2009 Dec 8. J Biol Chem. 2010. PMID: 19996319 Free PMC article.

6

Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.

Bélanger AS, Tojcic J, Harvey M, Guillemette C. Bélanger AS, et al. Among authors: harvey m. BMC Mol Biol. 2010 Jan 22;11:9. doi: 10.1186/1471-2199-11-9. BMC Mol Biol. 2010. PMID: 20096102 Free PMC article.

7

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

Bellemare J, Rouleau M, Girard H, Harvey M, Guillemette C. Bellemare J, et al. Among authors: harvey m. Drug Metab Dispos. 2010 Oct;38(10):1785-9. doi: 10.1124/dmd.110.034835. Epub 2010 Jul 7. Drug Metab Dispos. 2010. PMID: 20610558

8

Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants.

Ménard V, Eap O, Roberge J, Harvey M, Lévesque E, Guillemette C. Ménard V, et al. Among authors: harvey m. Pharmacogenet Genomics. 2011 Oct;21(10):631-41. doi: 10.1097/FPC.0b013e3283498147. Pharmacogenet Genomics. 2011. PMID: 21881541

9

Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.

Lévesque E, Bélanger AS, Harvey M, Couture F, Jonker D, Innocenti F, Cecchin E, Toffoli G, Guillemette C. Lévesque E, et al. Among authors: harvey m. J Pharmacol Exp Ther. 2013 Apr;345(1):95-101. doi: 10.1124/jpet.112.202242. Epub 2013 Feb 5. J Pharmacol Exp Ther. 2013. PMID: 23386248 Free PMC article. Clinical Trial.

10

Alternative-splicing forms of the major phase II conjugating UGT1A gene negatively regulate glucuronidation in human carcinoma cell lines.

Bellemare J, Rouleau M, Harvey M, Têtu B, Guillemette C. Bellemare J, et al. Among authors: harvey m. Pharmacogenomics J. 2010 Oct;10(5):431-41. doi: 10.1038/tpj.2009.64. Epub 2009 Dec 8. Pharmacogenomics J. 2010. PMID: 19997083

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