Böttcher T - Search Results

1

Structurally refined beta-lactones as potent inhibitors of devastating bacterial virulence factors.

Böttcher T, Sieber SA. Böttcher T, et al. Chembiochem. 2009 Mar 2;10(4):663-6. doi: 10.1002/cbic.200800743. Chembiochem. 2009. PMID: 19206121

2

Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes.

Böttcher T, Sieber SA. Böttcher T, et al. Angew Chem Int Ed Engl. 2008;47(24):4600-3. doi: 10.1002/anie.200705768. Angew Chem Int Ed Engl. 2008. PMID: 18383487 No abstract available.

3

Beta-lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureus.

Böttcher T, Sieber SA. Böttcher T, et al. J Am Chem Soc. 2008 Nov 5;130(44):14400-1. doi: 10.1021/ja8051365. Epub 2008 Oct 11. J Am Chem Soc. 2008. PMID: 18847196

4

Beta-lactones decrease the intracellular virulence of Listeria monocytogenes in macrophages.

Böttcher T, Sieber SA. Böttcher T, et al. ChemMedChem. 2009 Aug;4(8):1260-3. doi: 10.1002/cmdc.200900157. ChemMedChem. 2009. PMID: 19472261 No abstract available.

5

Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria.

Böttcher T, Sieber SA. Böttcher T, et al. J Am Chem Soc. 2010 May 26;132(20):6964-72. doi: 10.1021/ja909150y. J Am Chem Soc. 2010. PMID: 20433172

6

The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds.

Orth R, Böttcher T, Sieber SA. Orth R, et al. Among authors: bottcher t. Chem Commun (Camb). 2010 Nov 28;46(44):8475-7. doi: 10.1039/c0cc02825h. Epub 2010 Oct 8. Chem Commun (Camb). 2010. PMID: 20936198

7

Development and characterization of improved β-lactone-based anti-virulence drugs targeting ClpP.

Zeiler E, Korotkov VS, Lorenz-Baath K, Böttcher T, Sieber SA. Zeiler E, et al. Among authors: bottcher t. Bioorg Med Chem. 2012 Jan 15;20(2):583-91. doi: 10.1016/j.bmc.2011.07.047. Epub 2011 Jul 29. Bioorg Med Chem. 2012. PMID: 21855356

8

Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization.

Hackl MW, Lakemeyer M, Dahmen M, Glaser M, Pahl A, Lorenz-Baath K, Menzel T, Sievers S, Böttcher T, Antes I, Waldmann H, Sieber SA. Hackl MW, et al. Among authors: bottcher t. J Am Chem Soc. 2015 Jul 8;137(26):8475-83. doi: 10.1021/jacs.5b03084. Epub 2015 Jun 29. J Am Chem Soc. 2015. PMID: 26083639

9

An Aromatic Hydroxyamide Attenuates Multiresistant Staphylococcus aureus Toxin Expression.

Vomacka J, Korotkov VS, Bauer B, Weinandy F, Kunzmann MH, Krysiak J, Baron O, Böttcher T, Lorenz-Baath K, Sieber SA. Vomacka J, et al. Among authors: bottcher t. Chemistry. 2016 Jan 26;22(5):1622-30. doi: 10.1002/chem.201503981. Epub 2016 Jan 8. Chemistry. 2016. PMID: 26748534

10

Natural products and their biological targets: proteomic and metabolomic labeling strategies.

Böttcher T, Pitscheider M, Sieber SA. Böttcher T, et al. Angew Chem Int Ed Engl. 2010 Apr 1;49(15):2680-98. doi: 10.1002/anie.200905352. Angew Chem Int Ed Engl. 2010. PMID: 20333627 Review.

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