Bardeesy N - Search Results

1

Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.

Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. Plentz R, et al. Among authors: bardeesy n. Gastroenterology. 2009 May;136(5):1741-9.e6. doi: 10.1053/j.gastro.2009.01.008. Epub 2009 Jan 14. Gastroenterology. 2009. PMID: 19208345 Free PMC article.

2

Dual inactivation of RB and p53 pathways in RAS-induced melanomas.

Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L. Bardeesy N, et al. Mol Cell Biol. 2001 Mar;21(6):2144-53. doi: 10.1128/MCB.21.6.2144-2153.2001. Mol Cell Biol. 2001. PMID: 11238948 Free PMC article.

3

The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.

Bardeesy N, Sharpless NE, DePinho RA, Merlino G. Bardeesy N, et al. Semin Cancer Biol. 2001 Jun;11(3):201-18. doi: 10.1006/scbi.2000.0371. Semin Cancer Biol. 2001. PMID: 11407945 Review.

4

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Bardeesy N, et al. Nature. 2002 Sep 12;419(6903):162-7. doi: 10.1038/nature01045. Nature. 2002. PMID: 12226664 Free article.

5

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, Horner J, Redston MS, DePinho RA. Aguirre AJ, et al. Among authors: bardeesy n. Genes Dev. 2003 Dec 15;17(24):3112-26. doi: 10.1101/gad.1158703. Epub 2003 Dec 17. Genes Dev. 2003. PMID: 14681207 Free PMC article.

6

Telomere induced senescence: end game signaling.

Hezel AF, Bardeesy N, Maser RS. Hezel AF, et al. Among authors: bardeesy n. Curr Mol Med. 2005 Mar;5(2):145-52. doi: 10.2174/1566524053586563. Curr Mol Med. 2005. PMID: 15974867 Review.

7

Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.

Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y. Stanger BZ, et al. Among authors: bardeesy n. Cancer Cell. 2005 Sep;8(3):185-95. doi: 10.1016/j.ccr.2005.07.015. Cancer Cell. 2005. PMID: 16169464 Free article.

8

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.

Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Bardeesy N, et al. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5947-52. doi: 10.1073/pnas.0601273103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585505 Free PMC article.

9

Genetics and biology of pancreatic ductal adenocarcinoma.

Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Hezel AF, et al. Among authors: bardeesy n. Genes Dev. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606. Genes Dev. 2006. PMID: 16702400 Free article. Review.

10

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.

Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, DePinho RA. Bardeesy N, et al. Genes Dev. 2006 Nov 15;20(22):3130-46. doi: 10.1101/gad.1478706. Genes Dev. 2006. PMID: 17114584 Free PMC article.

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