Holst B - Search Results

1

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction.

Holst B, Egerod KL, Jin C, Petersen PS, Østergaard MV, Hald J, Sprinkel AM, Størling J, Mandrup-Poulsen T, Holst JJ, Thams P, Orskov C, Wierup N, Sundler F, Madsen OD, Schwartz TW. Holst B, et al. Among authors: holst jj. Endocrinology. 2009 Jun;150(6):2577-85. doi: 10.1210/en.2008-1250. Epub 2009 Feb 12. Endocrinology. 2009. PMID: 19213833 Free PMC article.

2

Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor.

Holst B, Zoffmann S, Elling CE, Hjorth SA, Schwartz TW. Holst B, et al. Mol Pharmacol. 1998 Jan;53(1):166-75. doi: 10.1124/mol.53.1.166. Mol Pharmacol. 1998. PMID: 9443945

3

Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor.

Rosenkilde MM, Lucibello M, Holst B, Schwartz TW. Rosenkilde MM, et al. Among authors: holst b. FEBS Lett. 1998 Nov 13;439(1-2):35-40. doi: 10.1016/s0014-5793(98)01331-3. FEBS Lett. 1998. PMID: 9849872 Free article.

4

Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor.

Elling CE, Thirstrup K, Holst B, Schwartz TW. Elling CE, et al. Among authors: holst b. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12322-7. doi: 10.1073/pnas.96.22.12322. Proc Natl Acad Sci U S A. 1999. PMID: 10535920 Free PMC article.

5

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor.

Holst B, Elling CE, Schwartz TW. Holst B, et al. Mol Pharmacol. 2000 Aug;58(2):263-70. doi: 10.1124/mol.58.2.263. Mol Pharmacol. 2000. PMID: 10908293

6

Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.

Holst B, Hastrup H, Raffetseder U, Martini L, Schwartz TW. Holst B, et al. J Biol Chem. 2001 Jun 8;276(23):19793-9. doi: 10.1074/jbc.M100621200. Epub 2001 Feb 22. J Biol Chem. 2001. PMID: 11279104 Free article.

7

Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.

Holst PJ, Rosenkilde MM, Manfra D, Chen SC, Wiekowski MT, Holst B, Cifire F, Lipp M, Schwartz TW, Lira SA. Holst PJ, et al. Among authors: holst b. J Clin Invest. 2001 Dec;108(12):1789-96. doi: 10.1172/JCI13622. J Clin Invest. 2001. PMID: 11748262 Free PMC article.

8

NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.

Martini L, Hastrup H, Holst B, Fraile-Ramos A, Marsh M, Schwartz TW. Martini L, et al. Among authors: holst b. Mol Pharmacol. 2002 Jul;62(1):30-7. doi: 10.1124/mol.62.1.30. Mol Pharmacol. 2002. PMID: 12065752

9

Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors.

Holst B, Elling CE, Schwartz TW. Holst B, et al. J Biol Chem. 2002 Dec 6;277(49):47662-70. doi: 10.1074/jbc.M202103200. Epub 2002 Sep 18. J Biol Chem. 2002. PMID: 12244039 Free article.

10

Molecular mechanism of agonism and inverse agonism in the melanocortin receptors: Zn(2+) as a structural and functional probe.

Holst B, Schwartz TW. Holst B, et al. Ann N Y Acad Sci. 2003 Jun;994:1-11. doi: 10.1111/j.1749-6632.2003.tb03156.x. Ann N Y Acad Sci. 2003. PMID: 12851292 Review.

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