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MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.
Gorog DA, Jabr RI, Tanno M, Sarafraz N, Clark JE, Fisher SG, Cao XB, Bellahcene M, Dighe K, Kabir AM, Quinlan RA, Kato K, Gaestel M, Marber MS, Heads RJ. Gorog DA, et al. Among authors: heads rj. Cell Stress Chaperones. 2009 Sep;14(5):477-89. doi: 10.1007/s12192-009-0101-5. Epub 2009 Feb 13. Cell Stress Chaperones. 2009. PMID: 19214782 Free PMC article.
Targeting p38-MAPK in the ischaemic heart: kill or cure?
Bassi R, Heads R, Marber MS, Clark JE. Bassi R, et al. Curr Opin Pharmacol. 2008 Apr;8(2):141-6. doi: 10.1016/j.coph.2008.01.002. Epub 2008 Mar 4. Curr Opin Pharmacol. 2008. PMID: 18289939 Review.
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia.
Tanno M, Bassi R, Gorog DA, Saurin AT, Jiang J, Heads RJ, Martin JL, Davis RJ, Flavell RA, Marber MS. Tanno M, et al. Among authors: heads rj. Circ Res. 2003 Aug 8;93(3):254-61. doi: 10.1161/01.RES.0000083490.43943.85. Epub 2003 Jun 26. Circ Res. 2003. PMID: 12829618
Loss of Protein Kinase Novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation, and exacerbated ischaemia-reperfusion injury.
Francois AA, Obasanjo-Blackshire K, Clark JE, Boguslavskyi A, Holt MR, Parker PJ, Marber MS, Heads RJ. Francois AA, et al. Among authors: heads rj. Cardiovasc Res. 2018 Jan 1;114(1):138-157. doi: 10.1093/cvr/cvx206. Cardiovasc Res. 2018. PMID: 29045568 Free PMC article.
46 results