Franchi L - Search Results

1

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Nuñez G. Franchi L, et al. Nat Immunol. 2009 Mar;10(3):241-7. doi: 10.1038/ni.1703. Nat Immunol. 2009. PMID: 19221555 Free PMC article. Review.

2

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.

Kanneganti TD, Ozören N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Núñez G. Kanneganti TD, et al. Among authors: franchi l. Nature. 2006 Mar 9;440(7081):233-6. doi: 10.1038/nature04517. Epub 2006 Jan 11. Nature. 2006. PMID: 16407888 Free article.

3

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes.

Ozören N, Masumoto J, Franchi L, Kanneganti TD, Body-Malapel M, Ertürk I, Jagirdar R, Zhu L, Inohara N, Bertin J, Coyle A, Grant EP, Núñez G. Ozören N, et al. Among authors: franchi l. J Immunol. 2006 Apr 1;176(7):4337-42. doi: 10.4049/jimmunol.176.7.4337. J Immunol. 2006. PMID: 16547271

4

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.

Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Núñez G. Franchi L, et al. Nat Immunol. 2006 Jun;7(6):576-82. doi: 10.1038/ni1346. Epub 2006 Apr 30. Nat Immunol. 2006. PMID: 16648852

5

Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense.

Franchi L, McDonald C, Kanneganti TD, Amer A, Núñez G. Franchi L, et al. J Immunol. 2006 Sep 15;177(6):3507-13. doi: 10.4049/jimmunol.177.6.3507. J Immunol. 2006. PMID: 16951308 Review.

6

Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.

Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozören N, Brady G, Meshinchi S, Jagirdar R, Gewirtz A, Akira S, Núñez G. Amer A, et al. Among authors: franchi l. J Biol Chem. 2006 Nov 17;281(46):35217-23. doi: 10.1074/jbc.M604933200. Epub 2006 Sep 19. J Biol Chem. 2006. PMID: 16984919 Free article.

7

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.

Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, Taraporewala ZF, Miller D, Patton JT, Inohara N, Núñez G. Kanneganti TD, et al. Among authors: franchi l. J Biol Chem. 2006 Dec 1;281(48):36560-8. doi: 10.1074/jbc.M607594200. Epub 2006 Sep 28. J Biol Chem. 2006. PMID: 17008311 Free article.

8

Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling.

Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, Franchi L, Vandenabeele P, Núñez G. Kanneganti TD, et al. Among authors: franchi l. Immunity. 2007 Apr;26(4):433-43. doi: 10.1016/j.immuni.2007.03.008. Epub 2007 Apr 12. Immunity. 2007. PMID: 17433728 Free article.

9

Caspase-1 inflammasomes in infection and inflammation.

Lamkanfi M, Kanneganti TD, Franchi L, Núñez G. Lamkanfi M, et al. Among authors: franchi l. J Leukoc Biol. 2007 Aug;82(2):220-5. doi: 10.1189/jlb.1206756. Epub 2007 Apr 18. J Leukoc Biol. 2007. PMID: 17442855 Free article. Review.

10

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

Franchi L, Kanneganti TD, Dubyak GR, Núñez G. Franchi L, et al. J Biol Chem. 2007 Jun 29;282(26):18810-8. doi: 10.1074/jbc.M610762200. Epub 2007 May 9. J Biol Chem. 2007. PMID: 17491021 Free article.

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