Muñoz-Planillo R - Search Results

1

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Nuñez G. Franchi L, et al. Nat Immunol. 2009 Mar;10(3):241-7. doi: 10.1038/ni.1703. Nat Immunol. 2009. PMID: 19221555 Free PMC article. Review.

2

The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation.

Lamkanfi M, Amer A, Kanneganti TD, Muñoz-Planillo R, Chen G, Vandenabeele P, Fortier A, Gros P, Núñez G. Lamkanfi M, et al. J Immunol. 2007 Jun 15;178(12):8022-7. doi: 10.4049/jimmunol.178.12.8022. J Immunol. 2007. PMID: 17548639

3

A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome.

Muñoz-Planillo R, Franchi L, Miller LS, Núñez G. Muñoz-Planillo R, et al. J Immunol. 2009 Sep 15;183(6):3942-8. doi: 10.4049/jimmunol.0900729. Epub 2009 Aug 28. J Immunol. 2009. PMID: 19717510 Free PMC article.

4

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G. Harder J, et al. J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7. J Immunol. 2009. PMID: 19812205 Free PMC article.

5

Inflammasomes as microbial sensors.

Franchi L, Muñoz-Planillo R, Reimer T, Eigenbrod T, Núñez G. Franchi L, et al. Eur J Immunol. 2010 Mar;40(3):611-5. doi: 10.1002/eji.200940180. Eur J Immunol. 2010. PMID: 20201013 Free article. Review.

6

Sensing and reacting to microbes through the inflammasomes.

Franchi L, Muñoz-Planillo R, Núñez G. Franchi L, et al. Nat Immunol. 2012 Mar 19;13(4):325-32. doi: 10.1038/ni.2231. Nat Immunol. 2012. PMID: 22430785 Free PMC article. Review.

7

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.

Muñoz-Planillo R, Kuffa P, Martínez-Colón G, Smith BL, Rajendiran TM, Núñez G. Muñoz-Planillo R, et al. Immunity. 2013 Jun 27;38(6):1142-53. doi: 10.1016/j.immuni.2013.05.016. Immunity. 2013. PMID: 23809161 Free PMC article.

8

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

He Y, Varadarajan S, Muñoz-Planillo R, Burberry A, Nakamura Y, Núñez G. He Y, et al. Among authors: munoz planillo r. J Biol Chem. 2014 Jan 10;289(2):1142-50. doi: 10.1074/jbc.M113.515080. Epub 2013 Nov 21. J Biol Chem. 2014. PMID: 24265316 Free PMC article.

9

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

Suzuki S, Franchi L, He Y, Muñoz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Núñez G. Suzuki S, et al. Among authors: munoz planillo r. PLoS Pathog. 2014 Feb 6;10(2):e1003926. doi: 10.1371/journal.ppat.1003926. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516390 Free PMC article.

10

Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Ozkurede U, Kim YG, Arindam C, Gale M Jr, Silverman RH, Colonna M, Akira S, Núñez G. Franchi L, et al. Among authors: munoz planillo r. J Immunol. 2014 Oct 15;193(8):4214-4222. doi: 10.4049/jimmunol.1400582. Epub 2014 Sep 15. J Immunol. 2014. PMID: 25225670 Free PMC article.

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