Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

418 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.
Jordan R, Goff A, Frimm A, Corrado ML, Hensley LE, Byrd CM, Mucker E, Shamblin J, Bolken TC, Wlazlowski C, Johnson W, Chapman J, Twenhafel N, Tyavanagimatt S, Amantana A, Chinsangaram J, Hruby DE, Huggins J. Jordan R, et al. Among authors: huggins j. Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223621 Free PMC article. Clinical Trial.
Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.
Huggins J, Goff A, Hensley L, Mucker E, Shamblin J, Wlazlowski C, Johnson W, Chapman J, Larsen T, Twenhafel N, Karem K, Damon IK, Byrd CM, Bolken TC, Jordan R, Hruby D. Huggins J, et al. Antimicrob Agents Chemother. 2009 Jun;53(6):2620-5. doi: 10.1128/AAC.00021-09. Epub 2009 Apr 6. Antimicrob Agents Chemother. 2009. PMID: 19349521 Free PMC article.
An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge.
Yang G, Pevear DC, Davies MH, Collett MS, Bailey T, Rippen S, Barone L, Burns C, Rhodes G, Tohan S, Huggins JW, Baker RO, Buller RL, Touchette E, Waller K, Schriewer J, Neyts J, DeClercq E, Jones K, Hruby D, Jordan R. Yang G, et al. Among authors: huggins jw. J Virol. 2005 Oct;79(20):13139-49. doi: 10.1128/JVI.79.20.13139-13149.2005. J Virol. 2005. PMID: 16189015 Free PMC article.
N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors.
Bailey TR, Rippin SR, Opsitnick E, Burns CJ, Pevear DC, Collett MS, Rhodes G, Tohan S, Huggins JW, Baker RO, Kern ER, Keith KA, Dai D, Yang G, Hruby D, Jordan R. Bailey TR, et al. Among authors: huggins jw. J Med Chem. 2007 Apr 5;50(7):1442-4. doi: 10.1021/jm061484y. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335190 Free PMC article.
Progression of pathogenic events in cynomolgus macaques infected with variola virus.
Wahl-Jensen V, Cann JA, Rubins KH, Huggins JW, Fisher RW, Johnson AJ, de Kok-Mercado F, Larsen T, Raymond JL, Hensley LE, Jahrling PB. Wahl-Jensen V, et al. Among authors: huggins jw. PLoS One. 2011;6(10):e24832. doi: 10.1371/journal.pone.0024832. Epub 2011 Oct 6. PLoS One. 2011. PMID: 21998632 Free PMC article.
418 results