Sopher BL - Search Results

1

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR. Young JE, et al. Among authors: sopher bl. J Neurosci. 2009 Feb 18;29(7):1987-97. doi: 10.1523/JNEUROSCI.4072-08.2009. J Neurosci. 2009. PMID: 19228953 Free PMC article.

2

Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein.

Sopher BL, Fukuchi K, Smith AC, Leppig KA, Furlong CE, Martin GM. Sopher BL, et al. Brain Res Mol Brain Res. 1994 Oct;26(1-2):207-17. doi: 10.1016/0169-328x(94)90092-2. Brain Res Mol Brain Res. 1994. PMID: 7854049

3

Selective neurotoxicity of COOH-terminal fragments of the beta-amyloid precursor protein.

Fukuchi K, Sopher B, Furlong CE, Smith AC, Dang N, Martin GM. Fukuchi K, et al. Neurosci Lett. 1993 May 14;154(1-2):145-8. doi: 10.1016/0304-3940(93)90192-n. Neurosci Lett. 1993. PMID: 8361630

4

Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells.

Kinoshita Y, Jarell AD, Flaman JM, Foltz G, Schuster J, Sopher BL, Irvin DK, Kanning K, Kornblum HI, Nelson PS, Hieter P, Morrison RS. Kinoshita Y, et al. Among authors: sopher bl. J Biol Chem. 2001 Mar 2;276(9):6656-65. doi: 10.1074/jbc.M008536200. Epub 2000 Nov 8. J Biol Chem. 2001. PMID: 11071894 Free article.

5

In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis.

Sopher BL, Myrick SB, Hong JY, Smith AC, La Spada AR. Sopher BL, et al. Gene. 2000 Dec 31;261(2):383-90. doi: 10.1016/s0378-1119(00)00508-4. Gene. 2000. PMID: 11167027

6

Genomic organization, chromosome location, and expression analysis of mouse beta-synuclein, a candidate for involvement in neurodegeneration.

Sopher BL, Koszdin KL, McClain ME, Myrick SB, Martinez RA, Smith AC, La Spada AR. Sopher BL, et al. Cytogenet Cell Genet. 2001;93(1-2):117-23. doi: 10.1159/000056962. Cytogenet Cell Genet. 2001. PMID: 11474193

7

Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.

La Spada AR, Fu YH, Sopher BL, Libby RT, Wang X, Li LY, Einum DD, Huang J, Possin DE, Smith AC, Martinez RA, Koszdin KL, Treuting PM, Ware CB, Hurley JB, Ptácek LJ, Chen S. La Spada AR, et al. Among authors: sopher bl. Neuron. 2001 Sep 27;31(6):913-27. doi: 10.1016/s0896-6273(01)00422-6. Neuron. 2001. PMID: 11580893 Free article.

8

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

Garden GA, Libby RT, Fu YH, Kinoshita Y, Huang J, Possin DE, Smith AC, Martinez RA, Fine GC, Grote SK, Ware CB, Einum DD, Morrison RS, Ptacek LJ, Sopher BL, La Spada AR. Garden GA, et al. Among authors: sopher bl. J Neurosci. 2002 Jun 15;22(12):4897-905. doi: 10.1523/JNEUROSCI.22-12-04897.2002. J Neurosci. 2002. PMID: 12077187 Free PMC article.

9

Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.

Chen S, Peng GH, Wang X, Smith AC, Grote SK, Sopher BL, La Spada AR. Chen S, et al. Among authors: sopher bl. Hum Mol Genet. 2004 Jan 1;13(1):53-67. doi: 10.1093/hmg/ddh005. Epub 2003 Nov 12. Hum Mol Genet. 2004. PMID: 14613968

10

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration.

Sopher BL, Thomas PS Jr, LaFevre-Bernt MA, Holm IE, Wilke SA, Ware CB, Jin LW, Libby RT, Ellerby LM, La Spada AR. Sopher BL, et al. Neuron. 2004 Mar 4;41(5):687-99. doi: 10.1016/s0896-6273(04)00082-0. Neuron. 2004. PMID: 15003169 Free article.

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