Zhuang X - Search Results

1

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.

Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, Zhang Z. Xiong H, et al. Among authors: zhuang x. J Clin Invest. 2009 Mar;119(3):650-60. doi: 10.1172/JCI37617. Epub 2009 Feb 23. J Clin Invest. 2009. PMID: 19229105 Free PMC article.

2

DJ-1 mRNA anatomical localization and cell type identification in the mouse brain.

Xie Z, Zhuang X, Chen L. Xie Z, et al. Among authors: zhuang x. Neurosci Lett. 2009 Nov 20;465(3):214-9. doi: 10.1016/j.neulet.2009.09.024. Epub 2009 Sep 17. Neurosci Lett. 2009. PMID: 19766170 Free PMC article.

3

A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration.

Chen L, Xie Z, Turkson S, Zhuang X. Chen L, et al. Among authors: zhuang x. J Neurosci. 2015 Jan 21;35(3):890-905. doi: 10.1523/JNEUROSCI.0089-14.2015. J Neurosci. 2015. PMID: 25609609 Free PMC article.

4

Transgenic mouse models of dopamine deficiency.

Chen L, Zhuang X. Chen L, et al. Among authors: zhuang x. Ann Neurol. 2003;54 Suppl 6:S91-102. doi: 10.1002/ana.10655. Ann Neurol. 2003. PMID: 12891659 Review.

5

Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice.

Yang W, Chen L, Ding Y, Zhuang X, Kang UJ. Yang W, et al. Among authors: zhuang x. Hum Mol Genet. 2007 Dec 1;16(23):2900-10. doi: 10.1093/hmg/ddm249. Epub 2007 Sep 6. Hum Mol Genet. 2007. PMID: 17823202

6

Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia.

Lin W, Wadlington NL, Chen L, Zhuang X, Brorson JR, Kang UJ. Lin W, et al. Among authors: zhuang x. J Neurosci. 2014 Feb 19;34(8):3079-89. doi: 10.1523/JNEUROSCI.2286-13.2014. J Neurosci. 2014. PMID: 24553947 Free PMC article.

7

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice.

Chen L, Cagniard B, Mathews T, Jones S, Koh HC, Ding Y, Carvey PM, Ling Z, Kang UJ, Zhuang X. Chen L, et al. Among authors: zhuang x. J Biol Chem. 2005 Jun 3;280(22):21418-26. doi: 10.1074/jbc.M413955200. Epub 2005 Mar 30. J Biol Chem. 2005. PMID: 15799973 Free article.

8

Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1.

Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, Tuder RM, Biswal S. Malhotra D, et al. Among authors: zhuang x. Am J Respir Crit Care Med. 2008 Sep 15;178(6):592-604. doi: 10.1164/rccm.200803-380OC. Epub 2008 Jun 12. Am J Respir Crit Care Med. 2008. Retraction in: Am J Respir Crit Care Med. 2016 Feb 1;193(3):344. doi: 10.1164/rccm.1933retraction PMID: 18556627 Free PMC article. Retracted.

9

PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.

Choi I, Kim J, Jeong HK, Kim B, Jou I, Park SM, Chen L, Kang UJ, Zhuang X, Joe EH. Choi I, et al. Among authors: zhuang x. Glia. 2013 May;61(5):800-12. doi: 10.1002/glia.22475. Epub 2013 Feb 26. Glia. 2013. PMID: 23440919 Free PMC article.

10

Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo.

Rappold PM, Cui M, Grima JC, Fan RZ, de Mesy-Bentley KL, Chen L, Zhuang X, Bowers WJ, Tieu K. Rappold PM, et al. Among authors: zhuang x. Nat Commun. 2014 Nov 5;5:5244. doi: 10.1038/ncomms6244. Nat Commun. 2014. PMID: 25370169 Free PMC article.

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