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Efficient approach to androstene-fused arylpyrazolines as potent antiproliferative agents. Experimental and theoretical studies of substituent effects on BF(3)-catalyzed intramolecular [3 + 2] cycloadditions of olefinic phenylhydrazones.
Frank E, Mucsi Z, Zupkó I, Réthy B, Falkay G, Schneider G, Wölfling J. Frank E, et al. Among authors: wolfling j. J Am Chem Soc. 2009 Mar 25;131(11):3894-904. doi: 10.1021/ja808636e. J Am Chem Soc. 2009. PMID: 19245200
An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.
Kovács D, Wölfling J, Szabó N, Szécsi M, Kovács I, Zupkó I, Frank E. Kovács D, et al. Among authors: wolfling j. Eur J Med Chem. 2013;70:649-60. doi: 10.1016/j.ejmech.2013.10.038. Epub 2013 Oct 22. Eur J Med Chem. 2013. PMID: 24211641
Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro.
Baji Á, Kovács F, Mótyán G, Schneider G, Wölfling J, Sinka I, Zupkó I, Ocsovszki I, Frank É. Baji Á, et al. Among authors: wolfling j. Steroids. 2017 Oct;126:35-49. doi: 10.1016/j.steroids.2017.08.003. Epub 2017 Aug 10. Steroids. 2017. PMID: 28803210
99 results