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Page 1
Affinity maturation by phage display.
Thie H, Voedisch B, Dübel S, Hust M, Schirrmann T. Thie H, et al. Methods Mol Biol. 2009;525:309-22, xv. doi: 10.1007/978-1-59745-554-1_16. Methods Mol Biol. 2009. PMID: 19252854
Phage display derived therapeutic antibodies.
Thie H, Meyer T, Schirrmann T, Hust M, Dübel S. Thie H, et al. Curr Pharm Biotechnol. 2008 Dec;9(6):439-46. doi: 10.2174/138920108786786349. Curr Pharm Biotechnol. 2008. PMID: 19075684 Review.
A human scFv antibody generation pipeline for proteome research.
Hust M, Meyer T, Voedisch B, Rülker T, Thie H, El-Ghezal A, Kirsch MI, Schütte M, Helmsing S, Meier D, Schirrmann T, Dübel S. Hust M, et al. Among authors: thie h. J Biotechnol. 2011 Apr 10;152(4):159-70. doi: 10.1016/j.jbiotec.2010.09.945. Epub 2010 Sep 29. J Biotechnol. 2011. PMID: 20883731
Rise and fall of an anti-MUC1 specific antibody.
Thie H, Toleikis L, Li J, von Wasielewski R, Bastert G, Schirrmann T, Esteves IT, Behrens CK, Fournes B, Fournier N, de Romeuf C, Hust M, Dübel S. Thie H, et al. PLoS One. 2011 Jan 14;6(1):e15921. doi: 10.1371/journal.pone.0015921. PLoS One. 2011. PMID: 21264246 Free PMC article.
When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.
Bradbury ARM, Trinklein ND, Thie H, Wilkinson IC, Tandon AK, Anderson S, Bladen CL, Jones B, Aldred SF, Bestagno M, Burrone O, Maynard J, Ferrara F, Trimmer JS, Görnemann J, Glanville J, Wolf P, Frenzel A, Wong J, Koh XY, Eng HY, Lane D, Lefranc MP, Clark M, Dübel S. Bradbury ARM, et al. Among authors: thie h. MAbs. 2018 May/Jun;10(4):539-546. doi: 10.1080/19420862.2018.1445456. Epub 2018 Mar 29. MAbs. 2018. PMID: 29485921 Free PMC article.