Cohen GM - Search Results

1

The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing.

Choi YE, Butterworth M, Malladi S, Duckett CS, Cohen GM, Bratton SB. Choi YE, et al. Among authors: cohen gm. J Biol Chem. 2009 May 8;284(19):12772-82. doi: 10.1074/jbc.M807550200. Epub 2009 Mar 3. J Biol Chem. 2009. PMID: 19258326 Free PMC article.

2

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.

MacFarlane M, Merrison W, Bratton SB, Cohen GM. MacFarlane M, et al. Among authors: cohen gm. J Biol Chem. 2002 Sep 27;277(39):36611-6. doi: 10.1074/jbc.M200317200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121969 Free article.

3

Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein.

Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Sun XM, et al. Among authors: cohen gm. J Biol Chem. 2002 Mar 29;277(13):11345-51. doi: 10.1074/jbc.M109893200. Epub 2002 Jan 18. J Biol Chem. 2002. PMID: 11801595 Free article.

4

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes.

Cain K, Bratton SB, Langlais C, Walker G, Brown DG, Sun XM, Cohen GM. Cain K, et al. Among authors: cohen gm. J Biol Chem. 2000 Mar 3;275(9):6067-70. doi: 10.1074/jbc.275.9.6067. J Biol Chem. 2000. PMID: 10692394 Free article.

5

XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.

Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM. Bratton SB, et al. Among authors: cohen gm. Cell Death Differ. 2002 Sep;9(9):881-92. doi: 10.1038/sj.cdd.4401069. Cell Death Differ. 2002. PMID: 12181739

6

The Apaf-1 apoptosome: a large caspase-activating complex.

Cain K, Bratton SB, Cohen GM. Cain K, et al. Among authors: cohen gm. Biochimie. 2002 Feb-Mar;84(2-3):203-14. doi: 10.1016/s0300-9084(02)01376-7. Biochimie. 2002. PMID: 12022951 Review.

7

Caspase activation inhibits proteasome function during apoptosis.

Sun XM, Butterworth M, MacFarlane M, Dubiel W, Ciechanover A, Cohen GM. Sun XM, et al. Among authors: cohen gm. Mol Cell. 2004 Apr 9;14(1):81-93. doi: 10.1016/s1097-2765(04)00156-x. Mol Cell. 2004. PMID: 15068805 Free article.

8

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes.

Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM. Bratton SB, et al. Among authors: cohen gm. EMBO J. 2001 Mar 1;20(5):998-1009. doi: 10.1093/emboj/20.5.998. EMBO J. 2001. PMID: 11230124 Free PMC article.

9

Caspase cascades in chemically-induced apoptosis.

Bratton SB, Cohen GM. Bratton SB, et al. Among authors: cohen gm. Adv Exp Med Biol. 2001;500:407-20. doi: 10.1007/978-1-4615-0667-6_63. Adv Exp Med Biol. 2001. PMID: 11764974 Review. No abstract available.

10

NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1.

Craxton A, Butterworth M, Harper N, Fairall L, Schwabe J, Ciechanover A, Cohen GM. Craxton A, et al. Among authors: cohen gm. Cell Death Differ. 2012 Sep;19(9):1424-34. doi: 10.1038/cdd.2012.16. Epub 2012 Feb 24. Cell Death Differ. 2012. PMID: 22361683 Free PMC article.

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