Ruble JC - Search Results

1

Synthesis of (-)-PNU-286607 by asymmetric cyclization of alkylidene barbiturates.

Ruble JC, Hurd AR, Johnson TA, Sherry DA, Barbachyn MR, Toogood PL, Bundy GL, Graber DR, Kamilar GM. Ruble JC, et al. J Am Chem Soc. 2009 Mar 25;131(11):3991-7. doi: 10.1021/ja808014h. J Am Chem Soc. 2009. PMID: 19260642

2

Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.

Miller AA, Bundy GL, Mott JE, Skepner JE, Boyle TP, Harris DW, Hromockyj AE, Marotti KR, Zurenko GE, Munzner JB, Sweeney MT, Bammert GF, Hamel JC, Ford CW, Zhong WZ, Graber DR, Martin GE, Han F, Dolak LA, Seest EP, Ruble JC, Kamilar GM, Palmer JR, Banitt LS, Hurd AR, Barbachyn MR. Miller AA, et al. Among authors: ruble jc. Antimicrob Agents Chemother. 2008 Aug;52(8):2806-12. doi: 10.1128/AAC.00247-08. Epub 2008 Jun 2. Antimicrob Agents Chemother. 2008. PMID: 18519725 Free PMC article.

3

Structure-activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors.

Ruble JC, Wakefield BD, Kamilar GM, Marotti KR, Melchior E, Sweeney MT, Zurenko GE, Romero DL. Ruble JC, et al. Bioorg Med Chem Lett. 2007 Jul 15;17(14):4040-3. doi: 10.1016/j.bmcl.2007.04.074. Epub 2007 Apr 27. Bioorg Med Chem Lett. 2007. PMID: 17561394

4

Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles.

Li J, Wakefield BD, Ruble JC, Stiff CM, Romero DL, Marotti KR, Sweeney MT, Zurenko GE, Rohrer DC, Thorarensen A. Li J, et al. Among authors: ruble jc. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2347-50. doi: 10.1016/j.bmcl.2006.12.055. Epub 2006 Dec 21. Bioorg Med Chem Lett. 2007. PMID: 17350254

5

Rhodium-Catalyzed Aldehyde Arylation via Formate-Mediated Transfer Hydrogenation: Beyond Metallic Reductants in Grignard/Nozaki-Hiyami-Kishi-Type Addition.

Swyka RA, Zhang W, Richardson J, Ruble JC, Krische MJ. Swyka RA, et al. Among authors: ruble jc. J Am Chem Soc. 2019 Feb 6;141(5):1828-1832. doi: 10.1021/jacs.8b13652. Epub 2019 Jan 29. J Am Chem Soc. 2019. PMID: 30693768 Free PMC article.

6

Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters.

Schwartz LA, Holmes M, Brito GA, Gonçalves TP, Richardson J, Ruble JC, Huang KW, Krische MJ. Schwartz LA, et al. Among authors: ruble jc. J Am Chem Soc. 2019 Feb 6;141(5):2087-2096. doi: 10.1021/jacs.8b11868. Epub 2019 Jan 25. J Am Chem Soc. 2019. PMID: 30681850 Free PMC article.

7

A Method for Identifying and Developing Functional Group Tolerant Catalytic Reactions: Application to the Buchwald-Hartwig Amination.

Richardson J, Ruble JC, Love EA, Berritt S. Richardson J, et al. Among authors: ruble jc. J Org Chem. 2017 Apr 7;82(7):3741-3750. doi: 10.1021/acs.joc.7b00201. Epub 2017 Mar 15. J Org Chem. 2017. PMID: 28245358

8

Improved synthesis of C4α- and C4β-methyl analogues of 2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate.

Henry SS, Brady MD, Laird DL, Ruble JC, Varie DL, Monn JA. Henry SS, et al. Among authors: ruble jc. Org Lett. 2012 Jun 1;14(11):2662-5. doi: 10.1021/ol300516y. Epub 2012 May 21. Org Lett. 2012. PMID: 22612291

9

Additives promote Noyori-type reductions of a β-keto-γ-lactam: asymmetric syntheses of serotonin norepinephrine reuptake inhibitors.

Magnus NA, Astleford BA, Laird DL, Maloney TD, McFarland AD, Rizzo JR, Ruble JC, Stephenson GA, Wepsiec JP. Magnus NA, et al. Among authors: ruble jc. J Org Chem. 2013 Jun 7;78(11):5768-74. doi: 10.1021/jo400589j. Epub 2013 May 20. J Org Chem. 2013. PMID: 23650960

10

Assembly of 4-aminoquinolines via palladium catalysis: a mild and convenient alternative to SNAr methodology.

Margolis BJ, Long KA, Laird DL, Ruble JC, Pulley SR. Margolis BJ, et al. Among authors: ruble jc. J Org Chem. 2007 Mar 16;72(6):2232-5. doi: 10.1021/jo062168u. Epub 2007 Feb 13. J Org Chem. 2007. PMID: 17295543

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

19 results

Search Page

Filters