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Page 1
Inhibition of tumor cell motility by the interferon-inducible GTPase MxA.
Mushinski JF, Nguyen P, Stevens LM, Khanna C, Lee S, Chung EJ, Lee MJ, Kim YS, Linehan WM, Horisberger MA, Trepel JB. Mushinski JF, et al. Among authors: linehan wm. J Biol Chem. 2009 May 29;284(22):15206-14. doi: 10.1074/jbc.M806324200. Epub 2009 Mar 18. J Biol Chem. 2009. PMID: 19297326 Free PMC article.
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma.
Riss J, Khanna C, Koo S, Chandramouli GV, Yang HH, Hu Y, Kleiner DE, Rosenwald A, Schaefer CF, Ben-Sasson SA, Yang L, Powell J, Kane DW, Star RA, Aprelikova O, Bauer K, Vasselli JR, Maranchie JK, Kohn KW, Buetow KH, Linehan WM, Weinstein JN, Lee MP, Klausner RD, Barrett JC. Riss J, et al. Among authors: linehan wm. Cancer Res. 2006 Jul 15;66(14):7216-24. doi: 10.1158/0008-5472.CAN-06-0040. Cancer Res. 2006. PMID: 16849569
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.
Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, Galindo C, Mollapour M, Scroggins B, Goode N, Lee MJ, Gourlay CW, Trepel J, Linehan WM, Neckers L. Sudarshan S, et al. Among authors: linehan wm. Mol Cell Biol. 2009 Aug;29(15):4080-90. doi: 10.1128/MCB.00483-09. Epub 2009 May 26. Mol Cell Biol. 2009. PMID: 19470762 Free PMC article.
The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.
Tong WH, Sourbier C, Kovtunovych G, Jeong SY, Vira M, Ghosh M, Romero VV, Sougrat R, Vaulont S, Viollet B, Kim YS, Lee S, Trepel J, Srinivasan R, Bratslavsky G, Yang Y, Linehan WM, Rouault TA. Tong WH, et al. Among authors: linehan wm. Cancer Cell. 2011 Sep 13;20(3):315-27. doi: 10.1016/j.ccr.2011.07.018. Cancer Cell. 2011. PMID: 21907923 Free PMC article.
817 results