Perera RM - Search Results

1

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes.

Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P. Zoncu R, et al. Among authors: perera rm. Cell. 2009 Mar 20;136(6):1110-21. doi: 10.1016/j.cell.2009.01.032. Cell. 2009. PMID: 19303853 Free PMC article.

2

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages.

Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D. Perera RM, et al. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19332-7. doi: 10.1073/pnas.0609795104. Epub 2006 Dec 8. Proc Natl Acad Sci U S A. 2006. PMID: 17158794 Free PMC article.

3

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

Zoncu R, Perera RM, Sebastian R, Nakatsu F, Chen H, Balla T, Ayala G, Toomre D, De Camilli PV. Zoncu R, et al. Among authors: perera rm. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3793-8. doi: 10.1073/pnas.0611733104. Epub 2007 Feb 27. Proc Natl Acad Sci U S A. 2007. PMID: 17360432 Free PMC article.

4

Internalization, intracellular trafficking, and biodistribution of monoclonal antibody 806: a novel anti-epidermal growth factor receptor antibody.

Perera RM, Zoncu R, Johns TG, Pypaert M, Lee FT, Mellman I, Old LJ, Toomre DK, Scott AM. Perera RM, et al. Neoplasia. 2007 Dec;9(12):1099-110. doi: 10.1593/neo.07721. Neoplasia. 2007. PMID: 18084617 Free PMC article.

5

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics.

Nakatsu F, Perera RM, Lucast L, Zoncu R, Domin J, Gertler FB, Toomre D, De Camilli P. Nakatsu F, et al. Among authors: perera rm. J Cell Biol. 2010 Aug 9;190(3):307-15. doi: 10.1083/jcb.201005018. Epub 2010 Aug 2. J Cell Biol. 2010. PMID: 20679431 Free PMC article.

6

The Lysosome as a Regulatory Hub.

Perera RM, Zoncu R. Perera RM, et al. Annu Rev Cell Dev Biol. 2016 Oct 6;32:223-253. doi: 10.1146/annurev-cellbio-111315-125125. Epub 2016 Aug 3. Annu Rev Cell Dev Biol. 2016. PMID: 27501449 Free PMC article. Review.

7

Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.

Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM, Perera RM, Covey DF, Nomura DK, Ory DS, Zoncu R. Castellano BM, et al. Among authors: perera rm. Science. 2017 Mar 24;355(6331):1306-1311. doi: 10.1126/science.aag1417. Science. 2017. PMID: 28336668 Free PMC article.

8

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C.

Davis OB, Shin HR, Lim CY, Wu EY, Kukurugya M, Maher CF, Perera RM, Ordonez MP, Zoncu R. Davis OB, et al. Among authors: perera rm. Dev Cell. 2021 Feb 8;56(3):260-276.e7. doi: 10.1016/j.devcel.2020.11.016. Epub 2020 Dec 11. Dev Cell. 2021. PMID: 33308480 Free PMC article.

9

Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth.

Gupta S, Yano J, Mercier V, Htwe HH, Shin HR, Rademaker G, Cakir Z, Ituarte T, Wen KW, Kim GE, Zoncu R, Roux A, Dawson DW, Perera RM. Gupta S, et al. Among authors: perera rm. Nat Cell Biol. 2021 Mar;23(3):232-242. doi: 10.1038/s41556-021-00644-7. Epub 2021 Mar 8. Nat Cell Biol. 2021. PMID: 33686253 Free PMC article.

10

Built to last: lysosome remodeling and repair in health and disease.

Zoncu R, Perera RM. Zoncu R, et al. Among authors: perera rm. Trends Cell Biol. 2022 Jul;32(7):597-610. doi: 10.1016/j.tcb.2021.12.009. Epub 2022 Feb 2. Trends Cell Biol. 2022. PMID: 35123838 Free PMC article. Review.

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