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Preclinical characterization of PF-00868554, a potent nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Shi ST, Herlihy KJ, Graham JP, Nonomiya J, Rahavendran SV, Skor H, Irvine R, Binford S, Tatlock J, Li H, Gonzalez J, Linton A, Patick AK, Lewis C. Shi ST, et al. Among authors: skor h. Antimicrob Agents Chemother. 2009 Jun;53(6):2544-52. doi: 10.1128/AAC.01599-08. Epub 2009 Mar 23. Antimicrob Agents Chemother. 2009. PMID: 19307358 Free PMC article.
Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor.
Li H, Tatlock J, Linton A, Gonzalez J, Jewell T, Patel L, Ludlum S, Drowns M, Rahavendran SV, Skor H, Hunter R, Shi ST, Herlihy KJ, Parge H, Hickey M, Yu X, Chau F, Nonomiya J, Lewis C. Li H, et al. Among authors: skor h. J Med Chem. 2009 Mar 12;52(5):1255-8. doi: 10.1021/jm8014537. J Med Chem. 2009. PMID: 19209845
A Plasma-Based Protein Marker Panel for Colorectal Cancer Detection Identified by Multiplex Targeted Mass Spectrometry.
Jones JJ, Wilcox BE, Benz RW, Babbar N, Boragine G, Burrell T, Christie EB, Croner LJ, Cun P, Dillon R, Kairs SN, Kao A, Preston R, Schreckengaust SR, Skor H, Smith WF, You J, Hillis WD, Agus DB, Blume JE. Jones JJ, et al. Among authors: skor h. Clin Colorectal Cancer. 2016 Jun;15(2):186-194.e13. doi: 10.1016/j.clcc.2016.02.004. Epub 2016 Mar 25. Clin Colorectal Cancer. 2016. PMID: 27237338 Free PMC article.
Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study.
Terry-Lorenzo R, Albrecht D, Crouch S, Wong R, Loewen G, Giri N, Skor H, Lin K, Sandiego CM, Pajonas M, Rabiner EA, Gunn RN, Russell DS, Haubenberger D. Terry-Lorenzo R, et al. Among authors: skor h. Neuropsychopharmacology. 2025 Jan 5. doi: 10.1038/s41386-024-02046-3. Online ahead of print. Neuropsychopharmacology. 2025. PMID: 39757283
13 results