Clardy J - Search Results

1

Colorimetric high-throughput screen for detection of heme crystallization inhibitors.

Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF. Rush MA, et al. Among authors: clardy j. Antimicrob Agents Chemother. 2009 Jun;53(6):2564-8. doi: 10.1128/AAC.01466-08. Epub 2009 Mar 23. Antimicrob Agents Chemother. 2009. PMID: 19307367 Free PMC article.

2

High-throughput Plasmodium falciparum growth assay for malaria drug discovery.

Baniecki ML, Wirth DF, Clardy J. Baniecki ML, et al. Among authors: clardy j. Antimicrob Agents Chemother. 2007 Feb;51(2):716-23. doi: 10.1128/AAC.01144-06. Epub 2006 Nov 20. Antimicrob Agents Chemother. 2007. PMID: 17116676 Free PMC article.

3

High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development.

Junker LM, Clardy J. Junker LM, et al. Among authors: clardy j. Antimicrob Agents Chemother. 2007 Oct;51(10):3582-90. doi: 10.1128/AAC.00506-07. Epub 2007 Jul 30. Antimicrob Agents Chemother. 2007. PMID: 17664319 Free PMC article.

4

Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.

Mazitschek R, Patel V, Wirth DF, Clardy J. Mazitschek R, et al. Among authors: clardy j. Bioorg Med Chem Lett. 2008 May 1;18(9):2809-12. doi: 10.1016/j.bmcl.2008.04.007. Epub 2008 Apr 7. Bioorg Med Chem Lett. 2008. PMID: 18430569 Free PMC article.

5

Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Patel V, et al. Among authors: clardy j. J Biol Chem. 2008 Dec 12;283(50):35078-85. doi: 10.1074/jbc.M804990200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842591 Free PMC article.

6

Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum.

Martyn DC, Ramirez AP, Beattie MJ, Cortese JF, Patel V, Rush MA, Woerpel KA, Clardy J. Martyn DC, et al. Among authors: clardy j. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6521-4. doi: 10.1016/j.bmcl.2008.10.083. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18993067

7

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.

Dong CK, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF. Dong CK, et al. Among authors: clardy j. Bioorg Med Chem Lett. 2009 Feb 1;19(3):972-5. doi: 10.1016/j.bmcl.2008.11.071. Epub 2008 Nov 24. Bioorg Med Chem Lett. 2009. PMID: 19097788 Free PMC article.

8

Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.

Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J. Patel V, et al. Among authors: clardy j. J Med Chem. 2009 Apr 23;52(8):2185-7. doi: 10.1021/jm801654y. J Med Chem. 2009. PMID: 19317450 Free PMC article.

9

Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum.

Martyn DC, Beletsky G, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Liang B, Clardy J. Martyn DC, et al. Among authors: clardy j. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5657-60. doi: 10.1016/j.bmcl.2009.08.024. Epub 2009 Aug 8. Bioorg Med Chem Lett. 2009. PMID: 19699641

10

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.

Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J. Martyn DC, et al. Among authors: clardy j. Bioorg Med Chem Lett. 2010 Jan 1;20(1):228-31. doi: 10.1016/j.bmcl.2009.10.133. Epub 2009 Oct 31. Bioorg Med Chem Lett. 2010. PMID: 19914064

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