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Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity.
Wilson NS, Behrens GM, Lundie RJ, Smith CM, Waithman J, Young L, Forehan SP, Mount A, Steptoe RJ, Shortman KD, de Koning-Ward TF, Belz GT, Carbone FR, Crabb BS, Heath WR, Villadangos JA. Wilson NS, et al. Among authors: heath wr. Nat Immunol. 2006 Feb;7(2):165-72. doi: 10.1038/ni1300. Epub 2006 Jan 15. Nat Immunol. 2006. PMID: 16415871
Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells.
Caminschi I, Ahmet F, Heger K, Brady J, Nutt SL, Vremec D, Pietersz S, Lahoud MH, Schofield L, Hansen DS, O'Keeffe M, Smyth MJ, Bedoui S, Davey GM, Villadangos JA, Heath WR, Shortman K. Caminschi I, et al. Among authors: heath wr. J Exp Med. 2007 Oct 29;204(11):2579-90. doi: 10.1084/jem.20071351. Epub 2007 Oct 8. J Exp Med. 2007. PMID: 17923506 Free PMC article.
Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells.
Lundie RJ, de Koning-Ward TF, Davey GM, Nie CQ, Hansen DS, Lau LS, Mintern JD, Belz GT, Schofield L, Carbone FR, Villadangos JA, Crabb BS, Heath WR. Lundie RJ, et al. Among authors: heath wr. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14509-14. doi: 10.1073/pnas.0806727105. Epub 2008 Sep 17. Proc Natl Acad Sci U S A. 2008. PMID: 18799734 Free PMC article.
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.
Lau LS, Fernandez-Ruiz D, Mollard V, Sturm A, Neller MA, Cozijnsen A, Gregory JL, Davey GM, Jones CM, Lin YH, Haque A, Engwerda CR, Nie CQ, Hansen DS, Murphy KM, Papenfuss AT, Miles JJ, Burrows SR, de Koning-Ward T, McFadden GI, Carbone FR, Crabb BS, Heath WR. Lau LS, et al. Among authors: heath wr. PLoS Pathog. 2014 May 22;10(5):e1004135. doi: 10.1371/journal.ppat.1004135. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24854165 Free PMC article.
Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.
Fernandez-Ruiz D, Ng WY, Holz LE, Ma JZ, Zaid A, Wong YC, Lau LS, Mollard V, Cozijnsen A, Collins N, Li J, Davey GM, Kato Y, Devi S, Skandari R, Pauley M, Manton JH, Godfrey DI, Braun A, Tay SS, Tan PS, Bowen DG, Koch-Nolte F, Rissiek B, Carbone FR, Crabb BS, Lahoud M, Cockburn IA, Mueller SN, Bertolino P, McFadden GI, Caminschi I, Heath WR. Fernandez-Ruiz D, et al. Among authors: heath wr. Immunity. 2016 Oct 18;45(4):889-902. doi: 10.1016/j.immuni.2016.08.011. Epub 2016 Sep 27. Immunity. 2016. PMID: 27692609 Free article.
264 results