Hart AC - Search Results

1

Acetylation targets mutant huntingtin to autophagosomes for degradation.

Jeong H, Then F, Melia TJ Jr, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Jeong H, et al. Among authors: hart ac. Cell. 2009 Apr 3;137(1):60-72. doi: 10.1016/j.cell.2009.03.018. Cell. 2009. PMID: 19345187 Free PMC article.

2

Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity.

Faber PW, Voisine C, King DC, Bates EA, Hart AC. Faber PW, et al. Among authors: hart ac. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17131-6. doi: 10.1073/pnas.262544899. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486229 Free PMC article.

3

Caenorhabditis elegans as a model system for triplet repeat diseases.

Voisine C, Hart AC. Voisine C, et al. Among authors: hart ac. Methods Mol Biol. 2004;277:141-60. doi: 10.1385/1-59259-804-8:141. Methods Mol Biol. 2004. PMID: 15201454

4

Selective inhibitors of death in mutant huntingtin cells.

Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Varma H, et al. Among authors: hart ac. Nat Chem Biol. 2007 Feb;3(2):99-100. doi: 10.1038/nchembio852. Epub 2006 Dec 31. Nat Chem Biol. 2007. PMID: 17195849

5

Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.

Voisine C, Varma H, Walker N, Bates EA, Stockwell BR, Hart AC. Voisine C, et al. Among authors: hart ac. PLoS One. 2007 Jun 6;2(6):e504. doi: 10.1371/journal.pone.0000504. PLoS One. 2007. PMID: 17551584 Free PMC article.

6

Inhibitors of metabolism rescue cell death in Huntington's disease models.

Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR. Varma H, et al. Among authors: hart ac. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14525-30. doi: 10.1073/pnas.0704482104. Epub 2007 Aug 28. Proc Natl Acad Sci U S A. 2007. PMID: 17726098 Free PMC article.

7

A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall LJ, Vance DE, Tzoneva M, Hart AC, Näär AM. Walker AK, et al. Among authors: hart ac. Cell. 2011 Nov 11;147(4):840-52. doi: 10.1016/j.cell.2011.09.045. Epub 2011 Oct 27. Cell. 2011. PMID: 22035958 Free PMC article.

8

Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.

Bates EA, Victor M, Jones AK, Shi Y, Hart AC. Bates EA, et al. Among authors: hart ac. J Neurosci. 2006 Mar 8;26(10):2830-8. doi: 10.1523/JNEUROSCI.3344-05.2006. J Neurosci. 2006. PMID: 16525063 Free PMC article.

9

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron.

Faber PW, Alter JR, MacDonald ME, Hart AC. Faber PW, et al. Among authors: hart ac. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):179-84. doi: 10.1073/pnas.96.1.179. Proc Natl Acad Sci U S A. 1999. PMID: 9874792 Free PMC article.

10

Dietary restriction involves NAD⁺ -dependent mechanisms and a shift toward oxidative metabolism.

Moroz N, Carmona JJ, Anderson E, Hart AC, Sinclair DA, Blackwell TK. Moroz N, et al. Among authors: hart ac. Aging Cell. 2014 Dec;13(6):1075-85. doi: 10.1111/acel.12273. Epub 2014 Sep 25. Aging Cell. 2014. PMID: 25257342 Free PMC article.

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