Kordower JH - Search Results

1

Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease.

Herzog CD, Brown L, Gammon D, Kruegel B, Lin R, Wilson A, Bolton A, Printz M, Gasmi M, Bishop KM, Kordower JH, Bartus RT. Herzog CD, et al. Among authors: kordower jh. Neurosurgery. 2009 Apr;64(4):602-12; discussion 612-3. doi: 10.1227/01.NEU.0000340682.06068.01. Neurosurgery. 2009. PMID: 19349823

2

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys.

Herzog CD, Dass B, Holden JE, Stansell J 3rd, Gasmi M, Tuszynski MH, Bartus RT, Kordower JH. Herzog CD, et al. Among authors: kordower jh. Mov Disord. 2007 Jun 15;22(8):1124-32. doi: 10.1002/mds.21503. Mov Disord. 2007. PMID: 17443702

3

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease.

Gasmi M, Brandon EP, Herzog CD, Wilson A, Bishop KM, Hofer EK, Cunningham JJ, Printz MA, Kordower JH, Bartus RT. Gasmi M, et al. Among authors: kordower jh. Neurobiol Dis. 2007 Jul;27(1):67-76. doi: 10.1016/j.nbd.2007.04.003. Epub 2007 Apr 19. Neurobiol Dis. 2007. PMID: 17532642

4

Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point.

Bartus RT, Herzog CD, Bishop K, Ostrove JM, Tuszynski M, Kordower JH, Gasmi M. Bartus RT, et al. Among authors: kordower jh. Parkinsonism Relat Disord. 2007;13 Suppl 3:S469-77. doi: 10.1016/S1353-8020(08)70052-X. Parkinsonism Relat Disord. 2007. PMID: 18267286 Review.

5

Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum.

Herzog CD, Dass B, Gasmi M, Bakay R, Stansell JE, Tuszynski M, Bankiewicz K, Chen EY, Chu Y, Bishop K, Kordower JH, Bartus RT. Herzog CD, et al. Among authors: kordower jh. Mol Ther. 2008 Oct;16(10):1737-44. doi: 10.1038/mt.2008.170. Epub 2008 Aug 26. Mol Ther. 2008. PMID: 18728639 Free article.

6

Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.

Bartus RT, Herzog CD, Chu Y, Wilson A, Brown L, Siffert J, Johnson EM Jr, Olanow CW, Mufson EJ, Kordower JH. Bartus RT, et al. Among authors: kordower jh. Mov Disord. 2011 Jan;26(1):27-36. doi: 10.1002/mds.23442. Epub 2010 Nov 18. Mov Disord. 2011. PMID: 21322017 Free PMC article.

7

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease.

Bartus RT, Brown L, Wilson A, Kruegel B, Siffert J, Johnson EM Jr, Kordower JH, Herzog CD. Bartus RT, et al. Among authors: kordower jh. Neurobiol Dis. 2011 Oct;44(1):38-52. doi: 10.1016/j.nbd.2011.05.026. Epub 2011 Jun 17. Neurobiol Dis. 2011. PMID: 21704161

8

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies.

Bartus RT, Kordower JH, Johnson EM Jr, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Bartus RT, et al. Among authors: kordower jh. Neurobiol Dis. 2015 Jun;78:162-71. doi: 10.1016/j.nbd.2015.03.023. Epub 2015 Apr 2. Neurobiol Dis. 2015. PMID: 25841760

9

Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.

Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J 3rd, Gasmi M, Bartus RT. Kordower JH, et al. Ann Neurol. 2006 Dec;60(6):706-15. doi: 10.1002/ana.21032. Ann Neurol. 2006. PMID: 17192932

10

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease.

Ramaswamy S, McBride JL, Herzog CD, Brandon E, Gasmi M, Bartus RT, Kordower JH. Ramaswamy S, et al. Among authors: kordower jh. Neurobiol Dis. 2007 May;26(2):375-84. doi: 10.1016/j.nbd.2007.01.003. Epub 2007 Jan 25. Neurobiol Dis. 2007. PMID: 17336076

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