Kruegel B - Search Results

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Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease.

Herzog CD, Brown L, Gammon D, Kruegel B, Lin R, Wilson A, Bolton A, Printz M, Gasmi M, Bishop KM, Kordower JH, Bartus RT. Herzog CD, et al. Among authors: kruegel b. Neurosurgery. 2009 Apr;64(4):602-12; discussion 612-3. doi: 10.1227/01.NEU.0000340682.06068.01. Neurosurgery. 2009. PMID: 19349823

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies.

Bartus RT, Kordower JH, Johnson EM Jr, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD. Bartus RT, et al. Among authors: kruegel br. Neurobiol Dis. 2015 Jun;78:162-71. doi: 10.1016/j.nbd.2015.03.023. Epub 2015 Apr 2. Neurobiol Dis. 2015. PMID: 25841760

Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating "clinical proof-of-concept" for AAV-neurturin (CERE-120) in Parkinson's disease.

Bartus RT, Baumann TL, Brown L, Kruegel BR, Ostrove JM, Herzog CD. Bartus RT, et al. Among authors: kruegel br. Neurobiol Aging. 2013 Jan;34(1):35-61. doi: 10.1016/j.neurobiolaging.2012.07.018. Epub 2012 Aug 24. Neurobiol Aging. 2013. PMID: 22926166 Review.

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120).

Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM Jr, Bartus RT. Herzog CD, et al. Among authors: kruegel br. Neurobiol Dis. 2013 Oct;58:38-48. doi: 10.1016/j.nbd.2013.04.011. Epub 2013 Apr 28. Neurobiol Dis. 2013. PMID: 23631873

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease.

Bartus RT, Brown L, Wilson A, Kruegel B, Siffert J, Johnson EM Jr, Kordower JH, Herzog CD. Bartus RT, et al. Among authors: kruegel b. Neurobiol Dis. 2011 Oct;44(1):38-52. doi: 10.1016/j.nbd.2011.05.026. Epub 2011 Jun 17. Neurobiol Dis. 2011. PMID: 21704161

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