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Spatiotemporal patterning during T cell activation is highly diverse.
Singleton KL, Roybal KT, Sun Y, Fu G, Gascoigne NR, van Oers NS, Wülfing C. Singleton KL, et al. Among authors: roybal kt. Sci Signal. 2009 Apr 7;2(65):ra15. doi: 10.1126/scisignal.2000199. Sci Signal. 2009. PMID: 19351954 Free PMC article.
CD4+ CAR T-cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR T-cell therapy.
Ledergor G, Fan Z, Wu K, McCarthy E, Hyrenius-Wittsten A, Starzinski A, Chang H, Bridge M, Kwek S, Cheung A, Bylsma S, Hansen E, Wolf J, Wong S, Shah N, Roybal KT, Martin T, Ye CJ, Fong L. Ledergor G, et al. Among authors: roybal kt. Blood Adv. 2024 Jul 9;8(13):3562-3575. doi: 10.1182/bloodadvances.2023012416. Blood Adv. 2024. PMID: 38574299 Free PMC article.
Naturally occurring T cell mutations enhance engineered T cell therapies.
Garcia J, Daniels J, Lee Y, Zhu I, Cheng K, Liu Q, Goodman D, Burnett C, Law C, Thienpont C, Alavi J, Azimi C, Montgomery G, Roybal KT, Choi J. Garcia J, et al. Among authors: roybal kt. Nature. 2024 Feb;626(7999):626-634. doi: 10.1038/s41586-024-07018-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326614
The CD3 zeta subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR-CD3 complex at the immunological synapse.
DeFord-Watts LM, Dougall DS, Belkaya S, Johnson BA, Eitson JL, Roybal KT, Barylko B, Albanesi JP, Wülfing C, van Oers NS. DeFord-Watts LM, et al. Among authors: roybal kt. J Immunol. 2011 Jun 15;186(12):6839-47. doi: 10.4049/jimmunol.1002721. Epub 2011 May 4. J Immunol. 2011. PMID: 21543646 Free PMC article.
49 results