Qiu Q - Search Results

1

Molecular analysis of the in vivo metabolism and biodistribution of metabolically and non-metabolically activated combi-molecules of the triazene class.

Qiu Q, Larroque AL, Gibbs B, Fang Y, Lakhrissi Y, Soucy JP, Mzengeza S, Rachid Z, Jean-Claude BJ. Qiu Q, et al. Drug Metab Lett. 2009 Jan;3(1):1-9. doi: 10.2174/187231209787176344. Drug Metab Lett. 2009. PMID: 19356110

2

[Combi-molecules: a global approach towards better chemoselectivity and chemosensitivity].

Matheson S, Qiu Q, Brahimi F, Dudouit F, Banerjee R, Rachid Z, Jean-Claude BJ. Matheson S, et al. Among authors: qiu q. Bull Cancer. 2004 Dec;91(12):911-5. Bull Cancer. 2004. PMID: 15634632 Free article. French.

3

The combi-targeting concept: evidence for the formation of a novel inhibitor in vivo.

Merayo N, Rachid Z, Qiu Q, Brahimi F, Jean-Claude BJ. Merayo N, et al. Among authors: qiu q. Anticancer Drugs. 2006 Feb;17(2):165-71. doi: 10.1097/00001813-200602000-00007. Anticancer Drugs. 2006. PMID: 16428934

4

The combi-targeting concept: in vitro and in vivo fragmentation of a stable combi-nitrosourea engineered to interact with the epidermal growth factor receptor while remaining DNA reactive.

Qiu Q, Domarkas J, Banerjee R, Merayo N, Brahimi F, McNamee JP, Gibbs BF, Jean-Claude BJ. Qiu Q, et al. Clin Cancer Res. 2007 Jan 1;13(1):331-40. doi: 10.1158/1078-0432.CCR-06-0812. Clin Cancer Res. 2007. PMID: 17200372

5

Novel nitrogen mustard-armed combi-molecules for the selective targeting of epidermal growth factor receptor overexperessing solid tumors: discovery of an unusual structure-activity relationship.

Rachid Z, Brahimi F, Qiu Q, Williams C, Hartley JM, Hartley JA, Jean-Claude BJ. Rachid Z, et al. Among authors: qiu q. J Med Chem. 2007 May 31;50(11):2605-8. doi: 10.1021/jm070144p. Epub 2007 May 2. J Med Chem. 2007. PMID: 17472358

6

Synthesis of water soluble bis-triazenoquinazolines: an unusual predicted mode of binding to the epidermal growth factor receptor tyrosine kinase.

Larroque AL, Peori B, Williams C, Fang YQ, Qiu Q, Rachid Z, Jean-Claude BJ. Larroque AL, et al. Among authors: qiu q. Chem Biol Drug Des. 2008 Apr;71(4):374-9. doi: 10.1111/j.1747-0285.2008.00638.x. Chem Biol Drug Des. 2008. PMID: 18324926

7

Characterization of the potency of epidermal growth factor (EGFR)-DNA targeting combi-molecules containing a hydrolabile carbamate at the 3-position of the triazene chain.

MacPhee M, Rachid Z, Todorova M, Qiu Q, Belinsky G, Jean-Claude BJ. MacPhee M, et al. Among authors: qiu q. Invest New Drugs. 2011 Oct;29(5):833-45. doi: 10.1007/s10637-010-9431-5. Epub 2010 Apr 29. Invest New Drugs. 2011. PMID: 20428924

8

In vitro and in vivo biodistribution of ZRS1, a stabilized type I N-acetoxymethyl carbamate-containing combi-molecule.

Golabi N, Rachid Z, Qiu Q, Huang Y, Jean-Claude BJ. Golabi N, et al. Among authors: qiu q. Drug Metab Lett. 2011 Apr;5(2):141-9. doi: 10.2174/187231211795305212. Drug Metab Lett. 2011. PMID: 21457144

9

A bioanalytical investigation on the exquisitely strong in vitro potency of the EGFR-DNA targeting type II combi-molecule ZR2003 and its mitigated in vivo antitumour activity.

Golabi N, Brahimi F, Huang Y, Rachid Z, Qiu Q, Larroque-Lombard AL, Jean-Claude BJ. Golabi N, et al. Among authors: qiu q. J Pharm Biomed Anal. 2011 Nov 1;56(3):592-9. doi: 10.1016/j.jpba.2011.06.013. Epub 2011 Jun 24. J Pharm Biomed Anal. 2011. PMID: 21764236

10

"Combi-targeting" mitozolomide: conferring novel signaling inhibitory properties to an abandoned DNA alkylating agent in the treatment of advanced prostate cancer.

Fang Y, Qiu Q, Domarkas J, Larroque-Lombard AL, Rao S, Rachid Z, Gibbs BF, Gao X, Jean-Claude BJ. Fang Y, et al. Among authors: qiu q. Prostate. 2012 Sep 1;72(12):1273-85. doi: 10.1002/pros.22475. Epub 2012 Jan 30. Prostate. 2012. PMID: 22290742

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