Johnstone RW - Search Results

1

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors.

Frew AJ, Johnstone RW, Bolden JE. Frew AJ, et al. Among authors: johnstone rw. Cancer Lett. 2009 Aug 8;280(2):125-33. doi: 10.1016/j.canlet.2009.02.042. Epub 2009 Apr 8. Cancer Lett. 2009. PMID: 19359091 Review.

2

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW. Ruefli AA, et al. Among authors: johnstone rw. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10833-8. doi: 10.1073/pnas.191208598. Epub 2001 Sep 4. Proc Natl Acad Sci U S A. 2001. PMID: 11535817 Free PMC article.

3

Apoptosis: a link between cancer genetics and chemotherapy.

Johnstone RW, Ruefli AA, Lowe SW. Johnstone RW, et al. Cell. 2002 Jan 25;108(2):153-64. doi: 10.1016/s0092-8674(02)00625-6. Cell. 2002. PMID: 11832206 Free article. Review.

4

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.

Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW. Ruefli AA, et al. Among authors: johnstone rw. Int J Cancer. 2002 May 10;99(2):292-8. doi: 10.1002/ijc.10327. Int J Cancer. 2002. PMID: 11979447

5

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer.

Johnstone RW. Johnstone RW. Nat Rev Drug Discov. 2002 Apr;1(4):287-99. doi: 10.1038/nrd772. Nat Rev Drug Discov. 2002. PMID: 12120280 Review.

6

Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: a work in progress.

Gabrielli BG, Johnstone RW, Saunders NA. Gabrielli BG, et al. Among authors: johnstone rw. Curr Cancer Drug Targets. 2002 Dec;2(4):337-53. doi: 10.2174/1568009023333818. Curr Cancer Drug Targets. 2002. PMID: 12470210 Review.

7

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

Johnstone RW, Licht JD. Johnstone RW, et al. Cancer Cell. 2003 Jul;4(1):13-8. doi: 10.1016/s1535-6108(03)00165-x. Cancer Cell. 2003. PMID: 12892709 Free article. Review. No abstract available.

8

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW. Peart MJ, et al. Among authors: johnstone rw. Cancer Res. 2003 Aug 1;63(15):4460-71. Cancer Res. 2003. PMID: 12907619

9

Histone-deacetylase inhibitors for the treatment of cancer.

Lindemann RK, Gabrielli B, Johnstone RW. Lindemann RK, et al. Among authors: johnstone rw. Cell Cycle. 2004 Jun;3(6):779-88. Epub 2004 Jun 14. Cell Cycle. 2004. PMID: 15153801 Review.

10

Histone deacetylase inhibitors specifically kill nonproliferating tumour cells.

Burgess A, Ruefli A, Beamish H, Warrener R, Saunders N, Johnstone R, Gabrielli B. Burgess A, et al. Oncogene. 2004 Sep 2;23(40):6693-701. doi: 10.1038/sj.onc.1207893. Oncogene. 2004. PMID: 15235588

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