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Non-competitive androgen receptor inhibition in vitro and in vivo.
Jones JO, Bolton EC, Huang Y, Feau C, Guy RK, Yamamoto KR, Hann B, Diamond MI. Jones JO, et al. Among authors: guy rk. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7233-8. doi: 10.1073/pnas.0807282106. Epub 2009 Apr 10. Proc Natl Acad Sci U S A. 2009. PMID: 19363158 Free PMC article.
A surface on the androgen receptor that allosterically regulates coactivator binding.
Estébanez-Perpiñá E, Arnold LA, Nguyen P, Rodrigues ED, Mar E, Bateman R, Pallai P, Shokat KM, Baxter JD, Guy RK, Webb P, Fletterick RJ. Estébanez-Perpiñá E, et al. Among authors: guy rk. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16074-9. doi: 10.1073/pnas.0708036104. Epub 2007 Oct 2. Proc Natl Acad Sci U S A. 2007. PMID: 17911242 Free PMC article.
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
De Leon JT, Iwai A, Feau C, Garcia Y, Balsiger HA, Storer CL, Suro RM, Garza KM, Lee S, Kim YS, Chen Y, Ning YM, Riggs DL, Fletterick RJ, Guy RK, Trepel JB, Neckers LM, Cox MB. De Leon JT, et al. Among authors: guy rk. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11878-83. doi: 10.1073/pnas.1105160108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730179 Free PMC article.
An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.
Atkinson JM, Shelat AA, Carcaboso AM, Kranenburg TA, Arnold LA, Boulos N, Wright K, Johnson RA, Poppleton H, Mohankumar KM, Féau C, Phoenix T, Gibson P, Zhu L, Tong Y, Eden C, Ellison DW, Priebe W, Koul D, Yung WK, Gajjar A, Stewart CF, Guy RK, Gilbertson RJ. Atkinson JM, et al. Among authors: guy rk. Cancer Cell. 2011 Sep 13;20(3):384-99. doi: 10.1016/j.ccr.2011.08.013. Cancer Cell. 2011. PMID: 21907928 Free PMC article.
175 results