Isomura H - Search Results

1

Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription.

Sato Y, Shirata N, Kudoh A, Iwahori S, Nakayama S, Murata T, Isomura H, Nishiyama Y, Tsurumi T. Sato Y, et al. Among authors: isomura h. Virology. 2009 May 25;388(1):204-11. doi: 10.1016/j.virol.2009.03.017. Epub 2009 Apr 16. Virology. 2009. PMID: 19375142 Free article.

2

Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication.

Kudoh A, Daikoku T, Sugaya Y, Isomura H, Fujita M, Kiyono T, Nishiyama Y, Tsurumi T. Kudoh A, et al. Among authors: isomura h. J Virol. 2004 Jan;78(1):104-15. doi: 10.1128/jvi.78.1.104-115.2004. J Virol. 2004. PMID: 14671092 Free PMC article.

3

Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment.

Kudoh A, Fujita M, Zhang L, Shirata N, Daikoku T, Sugaya Y, Isomura H, Nishiyama Y, Tsurumi T. Kudoh A, et al. Among authors: isomura h. J Biol Chem. 2005 Mar 4;280(9):8156-63. doi: 10.1074/jbc.M411405200. Epub 2004 Dec 15. J Biol Chem. 2005. PMID: 15611093 Free article.

4

Architecture of replication compartments formed during Epstein-Barr virus lytic replication.

Daikoku T, Kudoh A, Fujita M, Sugaya Y, Isomura H, Shirata N, Tsurumi T. Daikoku T, et al. Among authors: isomura h. J Virol. 2005 Mar;79(6):3409-18. doi: 10.1128/JVI.79.6.3409-3418.2005. J Virol. 2005. PMID: 15731235 Free PMC article.

5

Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication.

Isomura H, Stinski MF, Kudoh A, Daikoku T, Shirata N, Tsurumi T. Isomura H, et al. J Virol. 2005 Aug;79(15):9597-607. doi: 10.1128/JVI.79.15.9597-9607.2005. J Virol. 2005. PMID: 16014922 Free PMC article.

We previously demonstrated that the major immediate early (MIE) proximal enhancer containing one GC box and the TATA box containing promoter are minimal elements required for transcription and viral replication in human fibroblast cells (H. Isomura, T. Tsurumi, M. F …

We previously demonstrated that the major immediate early (MIE) proximal enhancer containing one GC box and the TATA box containing promoter …

6

Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.

Kudoh A, Daikoku T, Ishimi Y, Kawaguchi Y, Shirata N, Iwahori S, Isomura H, Tsurumi T. Kudoh A, et al. Among authors: isomura h. J Virol. 2006 Oct;80(20):10064-72. doi: 10.1128/JVI.00678-06. J Virol. 2006. PMID: 17005684 Free PMC article.

7

The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis.

Isomura H, Stinski MF, Kudoh A, Nakayama S, Iwahori S, Sato Y, Tsurumi T. Isomura H, et al. J Virol. 2007 Jun;81(12):6197-206. doi: 10.1128/JVI.00089-07. Epub 2007 Apr 4. J Virol. 2007. PMID: 17409154 Free PMC article.

8

Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein.

Iwahori S, Shirata N, Kawaguchi Y, Weller SK, Sato Y, Kudoh A, Nakayama S, Isomura H, Tsurumi T. Iwahori S, et al. Among authors: isomura h. J Virol. 2007 Sep;81(18):9653-64. doi: 10.1128/JVI.00568-07. Epub 2007 Jul 3. J Virol. 2007. PMID: 17609267 Free PMC article.

9

A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.

Isomura H, Stinski MF, Kudoh A, Nakayama S, Murata T, Sato Y, Iwahori S, Tsurumi T. Isomura H, et al. J Virol. 2008 Jan;82(2):849-58. doi: 10.1128/JVI.01593-07. Epub 2007 Nov 7. J Virol. 2008. PMID: 17989180 Free PMC article.

10

Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts.

Isomura H, Stinski MF, Kudoh A, Murata T, Nakayama S, Sato Y, Iwahori S, Tsurumi T. Isomura H, et al. J Virol. 2008 Feb;82(4):1638-46. doi: 10.1128/JVI.01917-07. Epub 2007 Dec 5. J Virol. 2008. PMID: 18057245 Free PMC article.

The UL44 gene product from the late viral promoter affects primarily viral gene expression at late times after infection rather than viral DNA synthesis (H. Isomura, M. F. Stinski, A. Kudoh, S. Nakayama, S. Iwahori, Y. Sato, and T. Tsurumi, J. ...

The UL44 gene product from the late viral promoter affects primarily viral gene expression at late times after infection rather than viral D …

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