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The mechanism of topoisomerase I poisoning by a camptothecin analog.
Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB Jr, Stewart L. Staker BL, et al. Among authors: stewart l. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15387-92. doi: 10.1073/pnas.242259599. Epub 2002 Nov 8. Proc Natl Acad Sci U S A. 2002. PMID: 12426403 Free PMC article.
Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex.
Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Staker BL, et al. Among authors: stewart l. J Med Chem. 2005 Apr 7;48(7):2336-45. doi: 10.1021/jm049146p. J Med Chem. 2005. PMID: 15801827
Annu. Rev. Biochem. 2001, 70, 369-413. Stewart, L.; et al. Science 1998, 729, 1534-1541.) We report the X-ray crystal structures of the human top1-DNA complex bound with camptothecin and representative members of the indenoisoquinoline and indolocarbazole classes of …
Annu. Rev. Biochem. 2001, 70, 369-413. Stewart, L.; et al. Science 1998, 729, 1534-1541.) We report the X-ray crystal structur …
Gene Composer in a structural genomics environment.
Lorimer D, Raymond A, Mixon M, Burgin A, Staker B, Stewart L. Lorimer D, et al. Among authors: stewart l. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):985-91. doi: 10.1107/S1744309111027424. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904038 Free PMC article.
Gene design, cloning and protein-expression methods for high-value targets at the Seattle Structural Genomics Center for Infectious Disease.
Raymond A, Haffner T, Ng N, Lorimer D, Staker B, Stewart L. Raymond A, et al. Among authors: stewart l. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):992-7. doi: 10.1107/S1744309111026698. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904039 Free PMC article.
The Protein Maker: an automated system for high-throughput parallel purification.
Smith ER, Begley DW, Anderson V, Raymond AC, Haffner TE, Robinson JI, Edwards TE, Duncan N, Gerdts CJ, Mixon MB, Nollert P, Staker BL, Stewart LJ. Smith ER, et al. Among authors: stewart lj. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1015-21. doi: 10.1107/S1744309111028776. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904043 Free PMC article.
1,671 results