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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.
Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW. Ellis L, et al. Among authors: scott cl. Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21. Blood. 2009. PMID: 19383971 Free PMC article.
Role of the chromobox protein CBX7 in lymphomagenesis.
Scott CL, Gil J, Hernando E, Teruya-Feldstein J, Narita M, Martínez D, Visakorpi T, Mu D, Cordon-Cardo C, Peters G, Beach D, Lowe SW. Scott CL, et al. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5389-94. doi: 10.1073/pnas.0608721104. Epub 2007 Mar 20. Proc Natl Acad Sci U S A. 2007. PMID: 17374722 Free PMC article.
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma.
Lindemann RK, Newbold A, Whitecross KF, Cluse LA, Frew AJ, Ellis L, Williams S, Wiegmans AP, Dear AE, Scott CL, Pellegrini M, Wei A, Richon VM, Marks PA, Lowe SW, Smyth MJ, Johnstone RW. Lindemann RK, et al. Among authors: scott cl. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8071-6. doi: 10.1073/pnas.0702294104. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2007. PMID: 17470784 Free PMC article.
276 results