Keith WN - Search Results

1

The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma.

Sitaram RT, Cairney CJ, Grabowski P, Keith WN, Hallberg B, Ljungberg B, Roos G. Sitaram RT, et al. Among authors: keith wn. Int J Cancer. 2009 Aug 15;125(4):783-90. doi: 10.1002/ijc.24335. Int J Cancer. 2009. PMID: 19384955

2

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression.

Lafferty-Whyte K, Bilsland A, Hoare SF, Burns S, Zaffaroni N, Cairney CJ, Keith WN. Lafferty-Whyte K, et al. Among authors: keith wn. Neoplasia. 2010 May;12(5):405-14. doi: 10.1593/neo.10180. Neoplasia. 2010. PMID: 20454512 Free PMC article.

3

Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures.

Degerman S, Siwicki JK, Osterman P, Lafferty-Whyte K, Keith WN, Roos G. Degerman S, et al. Among authors: keith wn. Aging Cell. 2010 Apr;9(2):220-35. doi: 10.1111/j.1474-9726.2010.00550.x. Aging Cell. 2010. PMID: 20089118 Free article.

4

Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity.

Cairney CJ, Keith WN. Cairney CJ, et al. Among authors: keith wn. Biochimie. 2008 Jan;90(1):13-23. doi: 10.1016/j.biochi.2007.07.025. Epub 2007 Aug 6. Biochimie. 2008. PMID: 17854971 Review.

5

High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma.

Cairney CJ, Hoare SF, Daidone MG, Zaffaroni N, Keith WN. Cairney CJ, et al. Among authors: keith wn. Br J Cancer. 2008 Apr 22;98(8):1467-74. doi: 10.1038/sj.bjc.6604328. Epub 2008 Apr 15. Br J Cancer. 2008. PMID: 18414473 Free PMC article.

6

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

Lafferty-Whyte K, Cairney CJ, Will MB, Serakinci N, Daidone MG, Zaffaroni N, Bilsland A, Keith WN. Lafferty-Whyte K, et al. Among authors: keith wn. Oncogene. 2009 Oct 29;28(43):3765-74. doi: 10.1038/onc.2009.238. Epub 2009 Aug 17. Oncogene. 2009. PMID: 19684619 Free PMC article.

7

Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms.

Lafferty-Whyte K, Cairney CJ, Jamieson NB, Oien KA, Keith WN. Lafferty-Whyte K, et al. Among authors: keith wn. Biochim Biophys Acta. 2009 Apr;1792(4):341-52. doi: 10.1016/j.bbadis.2009.02.003. Epub 2009 Feb 12. Biochim Biophys Acta. 2009. PMID: 19419692 Free article. Review.

8

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.

Bilsland AE, Cairney CJ, Keith WN. Bilsland AE, et al. Among authors: keith wn. J Cell Mol Med. 2011 Feb;15(2):179-86. doi: 10.1111/j.1582-4934.2010.01253.x. J Cell Mol Med. 2011. PMID: 21199331 Free PMC article. Review.

9

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms.

Bilsland AE, Stevenson K, Liu Y, Hoare S, Cairney CJ, Roffey J, Keith WN. Bilsland AE, et al. Among authors: keith wn. PLoS Comput Biol. 2014 Feb 13;10(2):e1003448. doi: 10.1371/journal.pcbi.1003448. eCollection 2014 Feb. PLoS Comput Biol. 2014. PMID: 24550717 Free PMC article.

10

Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias.

Degerman S, Landfors M, Siwicki JK, Revie J, Borssén M, Evelönn E, Forestier E, Chrzanowska KH, Rydén P, Keith WN, Roos G. Degerman S, et al. Among authors: keith wn. Neoplasia. 2014 Jul;16(7):606-15. doi: 10.1016/j.neo.2014.07.001. Epub 2014 Jul 22. Neoplasia. 2014. PMID: 25065939 Free PMC article.

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