Hirano I - Search Results

1

CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma.

Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R. Takeshita A, et al. Among authors: hirano i. Br J Haematol. 2009 Jun;146(1):34-43. doi: 10.1111/j.1365-2141.2009.07701.x. Epub 2009 Apr 13. Br J Haematol. 2009. PMID: 19388933 Free article.

2

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells.

Takeshita A, Yamakage N, Shinjo K, Ono T, Hirano I, Nakamura S, Shigeno K, Tobita T, Maekawa M, Kiyoi H, Naoe T, Ohnishi K, Sugimoto Y, Ohno R. Takeshita A, et al. Among authors: hirano i. Leukemia. 2009 Jul;23(7):1329-36. doi: 10.1038/leu.2009.77. Epub 2009 Apr 16. Leukemia. 2009. PMID: 19369961

3

KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells.

Nakamura S, Okinaka K, Hirano I, Ono T, Sugimoto Y, Shigeno K, Fujisawa S, Shinjo K, Ohnishi K. Nakamura S, et al. Among authors: hirano i. Leuk Res. 2008 Sep;32(9):1358-65. doi: 10.1016/j.leukres.2008.02.012. Epub 2008 Apr 2. Leuk Res. 2008. PMID: 18384876

4

HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells.

Sugimoto Y, Nakamura S, Okinaka K, Hirano I, Ono T, Shigeno K, Shinjo K, Ohnishi K. Sugimoto Y, et al. Among authors: hirano i. Leuk Res. 2008 Jun;32(6):962-71. doi: 10.1016/j.leukres.2007.11.034. Epub 2008 Jan 10. Leuk Res. 2008. PMID: 18190961

5

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.

Hirano I, Nakamura S, Yokota D, Ono T, Shigeno K, Fujisawa S, Shinjo K, Ohnishi K. Hirano I, et al. J Biol Chem. 2009 Aug 14;284(33):22155-22165. doi: 10.1074/jbc.M808182200. Epub 2009 Mar 4. J Biol Chem. 2009. PMID: 19261608 Free PMC article.

6

Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation.

Takemura T, Nakamura S, Yokota D, Hirano I, Ono T, Shigeno K, Fujisawa S, Ohnishi K. Takemura T, et al. Among authors: hirano i. J Biol Chem. 2010 Feb 26;285(9):6585-94. doi: 10.1074/jbc.M109.075788. Epub 2009 Dec 22. J Biol Chem. 2010. PMID: 20028985 Free PMC article.

7

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia.

Nakamura S, Hirano I, Okinaka K, Takemura T, Yokota D, Ono T, Shigeno K, Shibata K, Fujisawa S, Ohnishi K. Nakamura S, et al. Among authors: hirano i. Carcinogenesis. 2010 Nov;31(11):2012-21. doi: 10.1093/carcin/bgq185. Epub 2010 Sep 7. Carcinogenesis. 2010. PMID: 20823107

8

Down-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression.

Nakamura S, Yokota D, Tan L, Nagata Y, Takemura T, Hirano I, Shigeno K, Shibata K, Fujisawa S, Ohnishi K. Nakamura S, et al. Among authors: hirano i. Int J Cancer. 2012 Mar 1;130(5):1046-59. doi: 10.1002/ijc.26065. Epub 2011 May 9. Int J Cancer. 2012. PMID: 21400515

9

Small GTPase RAB45-mediated p38 activation in apoptosis of chronic myeloid leukemia progenitor cells.

Nakamura S, Takemura T, Tan L, Nagata Y, Yokota D, Hirano I, Shigeno K, Shibata K, Fujie M, Fujisawa S, Ohnishi K. Nakamura S, et al. Among authors: hirano i. Carcinogenesis. 2011 Dec;32(12):1758-72. doi: 10.1093/carcin/bgr205. Epub 2011 Sep 1. Carcinogenesis. 2011. PMID: 21890458

10

Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.

Nakamura S, Yamashita M, Yokota D, Hirano I, Ono T, Fujie M, Shibata K, Niimi T, Suyama T, Maddali K, Asai K, Yamashita J, Iguchi Y, Ohnishi K. Nakamura S, et al. Among authors: hirano i. Invest New Drugs. 2010 Aug;28(4):381-91. doi: 10.1007/s10637-009-9255-3. Epub 2009 May 14. Invest New Drugs. 2010. PMID: 19436953

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