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Toxicity testing by category for 30,000 chemicals?
van Leeuwen K, Schaafsma G. van Leeuwen K, et al. Among authors: schaafsma g. Nature. 2009 Nov 5;462(7269):34. doi: 10.1038/462034c. Nature. 2009. PMID: 19890306 No abstract available.
BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.
Estupiñán HY, Wang Q, Berglöf A, Schaafsma GCP, Shi Y, Zhou L, Mohammad DK, Yu L, Vihinen M, Zain R, Smith CIE. Estupiñán HY, et al. Among authors: schaafsma gcp. Leukemia. 2021 May;35(5):1317-1329. doi: 10.1038/s41375-021-01123-6. Epub 2021 Feb 1. Leukemia. 2021. PMID: 33526860 Free PMC article.
Representativeness of variation benchmark datasets.
Schaafsma GCP, Vihinen M. Schaafsma GCP, et al. BMC Bioinformatics. 2018 Nov 29;19(1):461. doi: 10.1186/s12859-018-2478-6. BMC Bioinformatics. 2018. PMID: 30497376 Free PMC article.
96 results