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TCR affinity and negative regulation limit autoimmunity.
Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. Gronski MA, et al. Nat Med. 2004 Nov;10(11):1234-9. doi: 10.1038/nm1114. Epub 2004 Oct 3. Nat Med. 2004. PMID: 15467726 Free article.
The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.
Suh WK, Gajewska BU, Okada H, Gronski MA, Bertram EM, Dawicki W, Duncan GS, Bukczynski J, Plyte S, Elia A, Wakeham A, Itie A, Chung S, Da Costa J, Arya S, Horan T, Campbell P, Gaida K, Ohashi PS, Watts TH, Yoshinaga SK, Bray MR, Jordana M, Mak TW. Suh WK, et al. Among authors: gronski ma. Nat Immunol. 2003 Sep;4(9):899-906. doi: 10.1038/ni967. Epub 2003 Aug 17. Nat Immunol. 2003. PMID: 12925852
PKCtheta signals activation versus tolerance in vivo.
Berg-Brown NN, Gronski MA, Jones RG, Elford AR, Deenick EK, Odermatt B, Littman DR, Ohashi PS. Berg-Brown NN, et al. Among authors: gronski ma. J Exp Med. 2004 Mar 15;199(6):743-52. doi: 10.1084/jem.20031022. J Exp Med. 2004. PMID: 15024044 Free PMC article.
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses.
Mak TW, Shahinian A, Yoshinaga SK, Wakeham A, Boucher LM, Pintilie M, Duncan G, Gajewska BU, Gronski M, Eriksson U, Odermatt B, Ho A, Bouchard D, Whorisky JS, Jordana M, Ohashi PS, Pawson T, Bladt F, Tafuri A. Mak TW, et al. Nat Immunol. 2003 Aug;4(8):765-72. doi: 10.1038/ni947. Epub 2003 Jun 29. Nat Immunol. 2003. PMID: 12833154
13 results