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Two randomized, double-blind, placebo-controlled, dose-escalation phase 1 studies evaluating BTH1677, a 1, 3-1,6 beta glucan pathogen associated molecular pattern, in healthy volunteer subjects.
Halstenson CE, Shamp T, Gargano MA, Walsh RM, Patchen ML. Halstenson CE, et al. Among authors: shamp t. Invest New Drugs. 2016 Apr;34(2):202-15. doi: 10.1007/s10637-016-0325-z. Epub 2016 Feb 11. Invest New Drugs. 2016. PMID: 26865390 Free PMC article. Clinical Trial.
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, Wanner C, Krane V, Cass A, Craig J, Neal B, Jiang L, Hooi LS, Levin A, Agodoa L, Gaziano M, Kasiske B, Walker R, Massy ZA, Feldt-Rasmussen B, Krairittichai U, Ophascharoensuk V, Fellström B, Holdaas H, Tesar V, Wiecek A, Grobbee D, de Zeeuw D, Grönhagen-Riska C, Dasgupta T, Lewis D, Herrington W, Mafham M, Majoni W, Wallendszus K, Grimm R, Pedersen T, Tobert J, Armitage J, Baxter A, Bray C, Chen Y, Chen Z, Hill M, Knott C, Parish S, Simpson D, Sleight P, Young A, Collins R; SHARP Investigators. Baigent C, et al. Lancet. 2011 Jun 25;377(9784):2181-92. doi: 10.1016/S0140-6736(11)60739-3. Epub 2011 Jun 12. Lancet. 2011. PMID: 21663949 Free PMC article. Clinical Trial.
Effect of tipranavir-ritonavir on pharmacokinetics of raltegravir.
Hanley WD, Wenning LA, Moreau A, Kost JT, Mangin E, Shamp T, Stone JA, Gottesdiener KM, Wagner JA, Iwamoto M. Hanley WD, et al. Among authors: shamp t. Antimicrob Agents Chemother. 2009 Jul;53(7):2752-5. doi: 10.1128/AAC.01486-08. Epub 2009 Apr 27. Antimicrob Agents Chemother. 2009. PMID: 19398643 Free PMC article. Clinical Trial.