Induction chemotherapy with paclitaxel and cisplatin followed by radiotherapy for larynx organ preservation in advanced laryngeal and hypopharyngeal cancer offers moderate late toxicity outcome (DeLOS-I-trial).
Dietz A, Rudat V, Dreyhaupt J, Pritsch M, Hoppe F, Hagen R, Pfreundner L, Schröder U, Eckel H, Hess M, Schröder M, Schneider P, Jens B, Zenner HP, Werner JA, Engenhardt-Cabillic R, Vanselow B, Plinkert P, Niewald M, Kuhnt T, Budach W, Flentje M.
Dietz A, et al. Among authors: pfreundner l.
Eur Arch Otorhinolaryngol. 2009 Aug;266(8):1291-300. doi: 10.1007/s00405-008-0846-y. Epub 2008 Oct 30.
Eur Arch Otorhinolaryngol. 2009.
PMID: 18972123
Clinical Trial.