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Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. Among authors: lallemand b. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: lallemand bi. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
Denonne F, Atienzar F, Célanire S, Christophe B, Delannois F, Delaunoy C, Delporte ML, Durieu V, Gillard M, Lallemand B, Lamberty Y, Lorent G, Vanbellinghen A, Van Houtvin N, Verbois V, Provins L. Denonne F, et al. Among authors: lallemand b. ChemMedChem. 2010 Feb 1;5(2):206-12. doi: 10.1002/cmdc.200900446. ChemMedChem. 2010. PMID: 20043314 No abstract available.
Discovery of heterocyclic nonacetamide synaptic vesicle protein 2A (SV2A) ligands with single-digit nanomolar potency: opening avenues towards the first SV2A positron emission tomography (PET) ligands.
Mercier J, Archen L, Bollu V, Carré S, Evrard Y, Jnoff E, Kenda B, Lallemand B, Michel P, Montel F, Moureau F, Price N, Quesnel Y, Sauvage X, Valade A, Provins L. Mercier J, et al. Among authors: lallemand b. ChemMedChem. 2014 Apr;9(4):693-8. doi: 10.1002/cmdc.201300482. Epub 2014 Jan 20. ChemMedChem. 2014. PMID: 24446373
5-HT7 Receptor Antagonists with an Unprecedented Selectivity Profile.
Ates A, Burssens P, Lorthioir O, Lo Brutto P, Dehon G, Keyaerts J, Coloretti F, Lallemand B, Verbois V, Gillard M, Vermeiren C. Ates A, et al. Among authors: lallemand b. ChemMedChem. 2018 Apr 23;13(8):795-802. doi: 10.1002/cmdc.201800026. Epub 2018 Mar 30. ChemMedChem. 2018. PMID: 29451954
Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.
Porter J, Lumb S, Franklin RJ, Gascon-Simorte JM, Calmiano M, Riche KL, Lallemand B, Keyaerts J, Edwards H, Maloney A, Delgado J, King L, Foley A, Lecomte F, Reuberson J, Meier C, Batchelor M. Porter J, et al. Among authors: lallemand b. Bioorg Med Chem Lett. 2009 May 15;19(10):2780-4. doi: 10.1016/j.bmcl.2009.03.110. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19369077
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