Blanchard R - Search Results

1

Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors.

Denlinger CS, Blanchard R, Xu L, Bernaards C, Litwin S, Spittle C, Berg DJ, McLaughlin S, Redlinger M, Dorr A, Hambleton J, Holden S, Kearns A, Kenkare-Mitra S, Lum B, Meropol NJ, O'Dwyer PJ. Denlinger CS, et al. Among authors: blanchard r. Cancer Chemother Pharmacol. 2009 Dec;65(1):97-105. doi: 10.1007/s00280-009-1008-7. Epub 2009 May 5. Cancer Chemother Pharmacol. 2009. PMID: 19415281 Free PMC article. Clinical Trial.

2

UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.

Carlini LE, Meropol NJ, Bever J, Andria ML, Hill T, Gold P, Rogatko A, Wang H, Blanchard RL. Carlini LE, et al. Clin Cancer Res. 2005 Feb 1;11(3):1226-36. Clin Cancer Res. 2005. PMID: 15709193 Clinical Trial.

3

Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan.

Nagar S, Blanchard RL. Nagar S, et al. Drug Metab Rev. 2006;38(3):393-409. doi: 10.1080/03602530600739835. Drug Metab Rev. 2006. PMID: 16877259 Review.

4

Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation.

Nagar S, Walther S, Blanchard RL. Nagar S, et al. Mol Pharmacol. 2006 Jun;69(6):2084-92. doi: 10.1124/mol.105.019240. Epub 2006 Mar 3. Mol Pharmacol. 2006. PMID: 16517757

5

Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells.

Nagar S, Zalatoris JJ, Blanchard RL. Nagar S, et al. Pharmacogenetics. 2004 Aug;14(8):487-99. doi: 10.1097/01.fpc.0000114771.78957.cb. Pharmacogenetics. 2004. PMID: 15284531

6

Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study.

Shatalova EG, Walther SE, Favorova OO, Rebbeck TR, Blanchard RL. Shatalova EG, et al. Among authors: blanchard rl. Breast Cancer Res. 2005;7(6):R909-21. doi: 10.1186/bcr1318. Epub 2005 Sep 21. Breast Cancer Res. 2005. PMID: 16280036 Free PMC article.

7

Treatment of advanced non-small cell lung cancer with very high-dose cisplatin combined with etoposide and mitomycin C.

Hesketh PJ, Tansan S, Caguioa PB, Hesketh A, Blanchard R, DiMartino N, Carney D. Hesketh PJ, et al. Among authors: blanchard r. Cancer. 1993 Feb 1;71(3):717-20. doi: 10.1002/1097-0142(19930201)71:3<717::aid-cncr2820710310>3.0.co;2-g. Cancer. 1993. PMID: 8381703 Clinical Trial.

8

Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer.

Baselga J, Cortés J, Kim SB, Im SA, Hegg R, Im YH, Roman L, Pedrini JL, Pienkowski T, Knott A, Clark E, Benyunes MC, Ross G, Swain SM; CLEOPATRA Study Group. Baselga J, et al. N Engl J Med. 2012 Jan 12;366(2):109-19. doi: 10.1056/NEJMoa1113216. Epub 2011 Dec 7. N Engl J Med. 2012. PMID: 22149875 Free PMC article. Clinical Trial.

9

Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk.

Rebbeck TR, Troxel AB, Wang Y, Walker AH, Panossian S, Gallagher S, Shatalova EG, Blanchard R, Bunin G, DeMichele A, Rubin SC, Baumgarten M, Berlin M, Schinnar R, Berlin JA, Strom BL. Rebbeck TR, et al. Among authors: blanchard r. J Natl Cancer Inst. 2006 Sep 20;98(18):1311-20. doi: 10.1093/jnci/djj360. J Natl Cancer Inst. 2006. PMID: 16985250

10

A question-based approach to adopting pharmacogenetics to understand risk for clinical variability in pharmacokinetics in early drug development.

Evers R, Blanchard RL, Warner AW, Cutler D, Agrawal NG, Shaw PM. Evers R, et al. Among authors: blanchard rl. Clin Pharmacol Ther. 2014 Sep;96(3):291-5. doi: 10.1038/clpt.2014.98. Clin Pharmacol Ther. 2014. PMID: 25141952

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