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Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
Nkrumah LJ, Riegelhaupt PM, Moura P, Johnson DJ, Patel J, Hayton K, Ferdig MT, Wellems TE, Akabas MH, Fidock DA. Nkrumah LJ, et al. Among authors: moura p. Mol Biochem Parasitol. 2009 Jun;165(2):122-31. doi: 10.1016/j.molbiopara.2009.01.011. Epub 2009 Jan 30. Mol Biochem Parasitol. 2009. PMID: 19428659 Free PMC article.
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. Yu M, et al. Among authors: moura pa. Cell Host Microbe. 2008 Dec 11;4(6):567-78. doi: 10.1016/j.chom.2008.11.001. Cell Host Microbe. 2008. PMID: 19064257 Free PMC article.
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.
Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA. Cowell AN, et al. Among authors: moura pa. Science. 2018 Jan 12;359(6372):191-199. doi: 10.1126/science.aan4472. Science. 2018. PMID: 29326268 Free PMC article.
Germline UBA1 Variant With Somatic Amplification in a Woman With Inflammatory Diseases and Myelodysplastic Syndrome.
Creignou M, Sirenko M, Moura PL, Mortera-Blanco T, Dimitriou M, Sander B, Domenico D, Arango Ossa JE, Tesi B, Beck DB, Woll P, Jacobsen SW, Papaemmanuil E, Bernard E, Hellström-Lindberg E. Creignou M, et al. Among authors: moura pl. Ann Intern Med. 2025 Jan 21. doi: 10.7326/L24-0125. Online ahead of print. Ann Intern Med. 2025. PMID: 39832370 No abstract available.
The impact of generative artificial intelligence (AI) on the development of personalized pharmaceuticals and the future of precision medicine.
Hillary VE, Gandhi Gopalsamy R, Santana LADM, de Jesus PC, de Souza JB, Silva DMRR, Moura PHM, Santos RS, Barreto MDS, Borges LP, Silva EED. Hillary VE, et al. Among authors: moura phm. EXCLI J. 2024 Nov 26;23:1459-1462. doi: 10.17179/excli2024-7915. eCollection 2024. EXCLI J. 2024. PMID: 39790560 Free PMC article. No abstract available.
311 results