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In vivo biodistribution of a highly attenuated recombinant vesicular stomatitis virus expressing HIV-1 Gag following intramuscular, intranasal, or intravenous inoculation.
Johnson JE, Coleman JW, Kalyan NK, Calderon P, Wright KJ, Obregon J, Ogin-Wilson E, Natuk RJ, Clarke DK, Udem SA, Cooper D, Hendry RM. Johnson JE, et al. Among authors: kalyan nk. Vaccine. 2009 May 14;27(22):2930-9. doi: 10.1016/j.vaccine.2009.03.006. Epub 2009 Mar 13. Vaccine. 2009. PMID: 19428903 Free PMC article.
Recombinant vesicular stomatitis virus vectors expressing herpes simplex virus type 2 gD elicit robust CD4+ Th1 immune responses and are protective in mouse and guinea pig models of vaginal challenge.
Natuk RJ, Cooper D, Guo M, Calderon P, Wright KJ, Nasar F, Witko S, Pawlyk D, Lee M, DeStefano J, Tummolo D, Abramovitz AS, Gangolli S, Kalyan N, Clarke DK, Hendry RM, Eldridge JH, Udem SA, Kowalski J. Natuk RJ, et al. J Virol. 2006 May;80(9):4447-57. doi: 10.1128/JVI.80.9.4447-4457.2006. J Virol. 2006. PMID: 16611905 Free PMC article.
Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates.
Clarke DK, Nasar F, Chong S, Johnson JE, Coleman JW, Lee M, Witko SE, Kotash CS, Abdullah R, Megati S, Luckay A, Nowak B, Lackner A, Price RE, Little P, Kalyan N, Randolf V, Javadian A, Zamb TJ, Parks CL, Egan MA, Eldridge J, Hendry M, Udem SA. Clarke DK, et al. J Virol. 2014 Jun;88(12):6690-701. doi: 10.1128/JVI.03441-13. Epub 2014 Apr 2. J Virol. 2014. PMID: 24696472 Free PMC article.
Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice.
Johnson JE, McNeil LK, Megati S, Witko SE, Roopchand VS, Obregon JH, Illenberger DM, Kotash CS, Nowak RM, Braunstein E, Yurgelonis I, Jansen KU, Kalyan NK, Sidhu MK. Johnson JE, et al. Among authors: kalyan nk. Immunol Lett. 2013 Feb;150(1-2):134-44. doi: 10.1016/j.imlet.2012.12.005. Epub 2012 Dec 20. Immunol Lett. 2013. PMID: 23261719
Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization.
Lubeck MD, Natuk R, Myagkikh M, Kalyan N, Aldrich K, Sinangil F, Alipanah S, Murthy SC, Chanda PK, Nigida SM Jr, Markham PD, Zolla-Pazner S, Steimer K, Wade M, Reitz MS Jr, Arthur LO, Mizutani S, Davis A, Hung PP, Gallo RC, Eichberg J, Robert-Guroff M. Lubeck MD, et al. Nat Med. 1997 Jun;3(6):651-8. doi: 10.1038/nm0697-651. Nat Med. 1997. PMID: 9176492
A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile.
Donald RGK, Flint M, Kalyan N, Johnson E, Witko SE, Kotash C, Zhao P, Megati S, Yurgelonis I, Lee PK, Matsuka YV, Severina E, Deatly A, Sidhu M, Jansen KU, Minton NP, Anderson AS. Donald RGK, et al. Microbiology (Reading). 2013 Jul;159(Pt 7):1254-1266. doi: 10.1099/mic.0.066712-0. Epub 2013 Apr 29. Microbiology (Reading). 2013. PMID: 23629868 Free PMC article.
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